Rabbit anti-Mouse Tetraspanin 30Cluster of Differentiation 63 (CD63) Polyclonal Antibody | anti-CD63 antibody

HRP-Linked Polyclonal Antibody to Tetraspanin 30Cluster of Differentiation 63 (CD63)

Cat. Num. AAA2126089

• Gene Names: Cd63; ME491; C75951; Tspan30
• Reactivity: Mouse
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
• Purity: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Synonyms: Tetraspanin 30Cluster of Differentiation 63 (CD63); Polyclonal Antibody; HRP-Linked Polyclonal Antibody to Tetraspanin 30Cluster of Differentiation 63 (CD63); CD63/Tetraspanin 30Cluster of Differentiation 63; TSPAN30; LAMP-3; ME491; MLA1; OMA81H; Melanoma 1 antigen; Granulophysin; Lysosomal-associated membrane protein 3; Ocular melanoma-associated antigen; anti-CD63 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Specificity: The antibody is a Rabbit polyclonal Antibody raised against Tetraspanin 30Cluster of Differentiation 63 (CD63). It has been selected for its ability to recognize CD63 in immunohistochemical staining and western blotting.
• Purity/Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Form/Format: Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Concentration: >=0.5mg/mL (Please refer to the vial label for the specific concentration.) (varies by lot)

• Applicable Applications for anti-CD63 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
• Application Notes: WB: 0.5-2ug/mL; IHC: 5-20ug/mL; ICC: 5-20ug/mL
• Immunogen: Recombinant proteins/RP
• Sequence of Immunogen: Ala103~Ile203, with N-terminal His Tag
• Organism Species: Mouse
• Conjugation: HRP
• Preparation and Storage: Store at 4 degree C for frequent use, -20 degree C for 24 months; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Product Categories/Family for anti-CD63 antibody

Signal transduction; CD & Adhesion molecule; Hematology; Developmental science; Primary, HRP-labeled

NCBI and Uniprot Product Information

• NCBI GI #: 110431344
• NCBI GeneID: 12512
• NCBI Accession #: NP_001036045.1
• NCBI GenBank Nucleotide #: NM_001042580.1
• UniProt Accession #: P41731
• Molecular Weight: 25,767 Da
• NCBI Official Full Name: CD63 antigen
• NCBI Official Synonym Full Names: CD63 antigen
• NCBI Official Symbol: Cd63
• NCBI Official Synonym Symbols: ME491; C75951; Tspan30
• NCBI Protein Information: CD63 antigen
• UniProt Protein Name: CD63 antigen
• Protein Family: CD63 antigen
• UniProt Gene Name: Cd63

Uniprot Description

Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.