Mouse DYNEIN CYTOPLASMIC Monoclonal Antibody | anti-DYNC1I2 antibody
MOUSE ANTI BOVINE DYNEIN CYTOPLASMIC 74kDa
Reactivity
Drosophila, Fish, Mouse, Rat, Sheep, Xenopus
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
DYNEIN CYTOPLASMIC; Monoclonal Antibody; MOUSE ANTI BOVINE DYNEIN CYTOPLASMIC 74kDa; anti-DYNC1I2 antibody
Host
Mouse
Reactivity
Drosophila, Fish, Mouse, Rat, Sheep, Xenopus
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
74.1
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
612
Applicable Applications for anti-DYNC1I2 antibody
Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Immunohistology - Frozen: Minimum Dilution: 1/10; Maximum Dilution: 1/100;
Western Blotting: Minimum Dilution: 1/1000; Maximum Dilution: 1/5000
Western Blotting: Minimum Dilution: 1/1000; Maximum Dilution: 1/5000
Perservative Stabilisers
0.1% Sodium Azide (NaN3)
Preparation
Preparation
Histology Positive Control Tissue
Cultured MDCK cells, NRR cells, N1E cells and PTK-1 cells.
Buffer Solution
Buffer Solution
Target Species
Bovine
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-DYNC1I2 antibody
reacts with all known forms of the 74 kDa intermediate chain subunit of mammalian cytoplasmic dynein. The antigenic site has been localized to the first 60 amino acids of the N-terminal portion of the molecule. Mouse anti Bovine dynein cytoplasmic 74kDA antibody, clone 74.1 immunoprecipitates the intermediate chain subunits under denaturing conditions and the entire dynein complex under native conditions.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68,377 Da
NCBI Official Full Name
cytoplasmic dynein 1 intermediate chain 2
NCBI Official Symbol
DYNC1I2
NCBI Protein Information
cytoplasmic dynein 1 intermediate chain 2; DH IC-2; cytoplasmic dynein intermediate chain 2; dynein intermediate chain 2, cytosolic
UniProt Protein Name
Cytoplasmic dynein 1 intermediate chain 2
Protein Family
UniProt Gene Name
DYNC1I2
UniProt Synonym Gene Names
DH IC-2
UniProt Entry Name
DC1I2_BOVIN
Uniprot Description
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes ().
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Product Notes
The DYNC1I2 dync1i2 (Catalog #AAA211301) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI BOVINE DYNEIN CYTOPLASMIC 74kDa reacts with Drosophila, Fish, Mouse, Rat, Sheep, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's DYNEIN CYTOPLASMIC can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB). Immunohistology - Frozen: Minimum Dilution: 1/10; Maximum Dilution: 1/100; Western Blotting: Minimum Dilution: 1/1000; Maximum Dilution: 1/5000. Researchers should empirically determine the suitability of the DYNC1I2 dync1i2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYNEIN CYTOPLASMIC, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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