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Mouse Gonadotropin Releasing Hormone (GnRH) ELISA Kit | GnRH elisa kit

Mouse Gonadotropin Releasing Hormone (GnRH) Mini Samples ELISA Kit

Gene Names
Mdk; MK; Mek
Reactivity
Mouse
Synonyms
Gonadotropin Releasing Hormone (GnRH); Mouse Gonadotropin Releasing Hormone (GnRH) Mini Samples ELISA Kit; GNRH1; GRH; LNRH; LHRH; LH-RH I; Luliberin; Luteinizing-Hormone Releasing Hormone; Progonadoliberin-1; Gonadoliberin I; Gonadorelin; GnRH-associated peptide 1; GnRH elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
140
Assay Type
Competitive Inhibition ELISA for Antigen Detection
Samples
Serum, plasma, Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Detection Range
12.35-1000pg/mL
Sensitivity
4.33pg/mL

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,434 Da
NCBI Official Full Name
midkine isoform a
NCBI Official Synonym Full Names
midkine
NCBI Official Symbol
Mdk
NCBI Official Synonym Symbols
MK; Mek
NCBI Protein Information
midkine
UniProt Protein Name
Midkine
UniProt Gene Name
Mdk
UniProt Synonym Gene Names
Mk; MK

NCBI Description

This gene encodes a secreted growth factor that belongs to the pleiotrophin/midkine heparin-binding protein family and functions in a variety of biological processes. The encoded cytokine promotes the growth, differentiation, survival and migration of several target cells including leucocytes involved in inflammation. This protein plays a role in the formation of scar tissue and intraperitoneal adhesions, and promotes neurite outgrowth and neuron survival. The protein encoded by this gene is associated with obesity and inhibition of insulin signaling in fat cells. A pseudogene of this gene is present on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Uniprot Description

MDK: Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development. Belongs to the pleiotrophin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2 E1|2 50.63 cM

Cellular Component: cell projection; cytoplasm

Molecular Function: heparin binding

Biological Process: adrenal gland development; behavioral fear response; cell migration; cerebellar granular layer development; cerebral cortex development; defecation; dentate gyrus development; hippocampus development; negative regulation of neuron apoptosis; positive regulation of transcription, DNA-dependent; regulation of behavior; response to wounding; short-term memory

Research Articles on GnRH

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Product Notes

The Mouse GnRH mdk (Catalog #AAA2087646) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2087646 ELISA Kit recognizes Mouse GnRH. It is sometimes possible for the material contained within the vial of "Gonadotropin Releasing Hormone (GnRH), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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