Microtubule Associated Protein 1B Recombinant Protein | MAP1B recombinant protein

Recombinant Microtubule Associated Protein 1B (MAP1B)

Cat. Num. AAA2034291

• Gene Names: MAP1B; MAP5; FUTSCH; PPP1R102
• Reactivity: Mouse
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >90%
• Synonyms: Microtubule Associated Protein 1B; Recombinant Microtubule Associated Protein 1B (MAP1B); FUTSCH; MAP5; MAP1B recombinant protein

• Host: E Coli
• Reactivity: Mouse
• Purity/Purification: >90%
• Sequence Length: 2468

• Applicable Applications for MAP1B recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Fragment: Asp2203~Leu2464
• Tag: Two N-terminal Tags, His-tag and T7-tag
• Expression System: Prokaryotic Expression
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 153945728
• NCBI GeneID: 4131
• NCBI Accession #: NP_005900.2
• NCBI GenBank Nucleotide #: NM_005909.3
• Molecular Weight: 32.0kDa
• NCBI Official Full Name: microtubule-associated protein 1B
• NCBI Official Synonym Full Names: microtubule associated protein 1B
• NCBI Official Symbol: MAP1B
• NCBI Official Synonym Symbols: MAP5; FUTSCH; PPP1R102
• NCBI Protein Information: microtubule-associated protein 1B
• UniProt Protein Name: Microtubule-associated protein 1B
• Protein Family: Methionine aminopeptidase
• UniProt Gene Name: MAP1B
• UniProt Synonym Gene Names: MAP-1B
• UniProt Entry Name: MAP1B_HUMAN

NCBI Description

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

MAP1B: the function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: cell junction; cytoplasm; cytosol; dendritic spine; microtubule; microtubule associated complex; photoreceptor outer segment; plasma membrane

Molecular Function: microtubule binding; protein binding; structural molecule activity

Biological Process: axon extension; cellular process; dendrite development; microtubule bundle formation; mitochondrion transport along microtubule; negative regulation of intracellular transport; positive regulation of axon extension