Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Urocortin 1 Polyclonal Antibody | anti-UCN1 antibody
Polyclonal Antibody to Urocortin 1 (UCN1)
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-TGVQDPN LRWSPGVRNQ GGGVRALLLL LAERFPRRAG SEPAGERQRR DDPPLSIDLT FHLLRTLLEL
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Intestine tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Intestine tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. Mice lacking the encoded protein exhibit a heightened anxiety-like behaviors and a significantly reduced acoustic startle response. [provided by RefSeq, Sep 2016]
Uniprot Description
UCN: Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5 B1|5 17.11 cM
Cellular Component: axon; axon terminus; cell soma; dendrite; extracellular region; perikaryon
Molecular Function: corticotropin-releasing hormone receptor 1 binding; corticotropin-releasing hormone receptor 2 binding; G-protein coupled receptor binding; histone deacetylase inhibitor activity; hormone activity
Biological Process: activation of protein kinase A activity; aerobic respiration; associative learning; drinking behavior; feeding behavior; learning and/or memory; negative regulation of apoptosis; negative regulation of appetite; negative regulation of blood pressure; negative regulation of cell size; negative regulation of hormone secretion; neuron projection development; neuropeptide signaling pathway; pancreatic juice secretion; positive regulation of cAMP biosynthetic process; positive regulation of cell growth; positive regulation of collagen biosynthetic process; positive regulation of corticotropin secretion; positive regulation of DNA replication; positive regulation of interleukin-6 production; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translation; positive regulation of vascular permeability; prepulse inhibition; regulation of synaptic transmission, glutamatergic; response to oxidative stress; response to starvation; sensory perception of sound; social behavior; startle response
Research Articles on UCN1
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Product Notes
The UCN1 ucn (Catalog #AAA2026354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Urocortin 1 (UCN1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Urocortin 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the UCN1 ucn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and GST-tag and its sequence is listed below. MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-TGV QDPN LRWSPGVRNQ GGGVRALLLL LAERFPRRAG SEPAGERQRR DDPPLSIDLT FHLLRTLLEL. It is sometimes possible for the material contained within the vial of "Urocortin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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