Angiopoietin Like Protein 2 (ANGPTL2) Recombinant Protein | ANGPTL2 recombinant protein

Recombinant Angiopoietin Like Protein 2 (ANGPTL2)

Cat. Num. AAA2012088

• Gene Names: ANGPTL2; ARP2; HARP
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Angiopoietin Like Protein 2 (ANGPTL2); Recombinant Angiopoietin Like Protein 2 (ANGPTL2); ANGPTL2 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSG SEF-STDKPSG PWRDCLQALE DGHDTSSIYL VKPENTNRLM QVWCDQRHDP GGWTVIQRRL DGSVNFFRNW ETYKQGFGNI DGEYWLGLEN IYWLTNQGNY KLLVTMEDWS GRKVFAEYAS FRLEPESEYY KLRLGRYHGN AGDSFTWHNG KQFTTLDRDH DVYTGNCAHY QKGGWWYNAC AHSNLNGVWY RGGHYRSRYQ DGVYWAEFRG GSYSLKKVVM MIRPNPNTFH
• Sequence Length: 493

• Applicable Applications for ANGPTL2 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Ser267~His493 (Accession # Q9UKU9) with N-terminal His-Tag
• Subcellular Location: Secreted
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Predicted Isoelectric Point: 7.3
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Sequence Information

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 6912236
• NCBI GeneID: 23452
• NCBI Accession #: NP_036230.1
• NCBI GenBank Nucleotide #: NM_012098.2
• UniProt Accession #: Q9UKU9; Q5JT58
• Molecular Weight: 28.3kDa
• NCBI Official Full Name: angiopoietin-related protein 2
• NCBI Official Synonym Full Names: angiopoietin-like 2
• NCBI Official Symbol: ANGPTL2
• NCBI Official Synonym Symbols: ARP2; HARP
• NCBI Protein Information: angiopoietin-related protein 2; angiopoietin-like protein 2
• UniProt Protein Name: Angiopoietin-related protein 2
• Protein Family: Angiopoietin-related protein
• UniProt Gene Name: ANGPTL2
• UniProt Synonym Gene Names: ARP2
• UniProt Entry Name: ANGL2_HUMAN

NCBI Description

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008]

Uniprot Description

ANGPTL2: Induces sprouting in endothelial cells through an autocrine and paracrine action.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: extracellular space

Molecular Function: receptor binding

Biological Process: multicellular organismal development