Sequence
Coiled Coil Domain Containing Protein 80 (CCDC80) Recombinant Protein | CCDC80 recombinant protein
Recombinant Coiled Coil Domain Containing Protein 80 (CCDC80)
Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition
Sequence
Sequence
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
Accurate Molecular Mass: 26kDa as determined by SDS-PAGE reducing conditions.
NCBI Description
estrogen regulated gene; overexpression correlates with mammary carcinogenesis [RGD, Feb 2006]
Uniprot Description
Function: Promotes cell adhesion and matrix assembly
By similarity.
Subunit structure: Binds to various extracellular matrix proteins
By similarity.
Subcellular location: Secreted › extracellular space › extracellular matrix
By similarity. Note: Isoform 2:Cytoplasm. Ref.1
Tissue specificity: Isoform 2is expressed in uterus, liver, lung, spleen, kidney, heart, bladder, skeletal muscle and brain (at protein level). Isoform 2is expressed very low in mammary gland and intestine (at protein level). Isoform 2is expressed in lactating mammary glands and mammary tumors (at protein level). Ubiquitous (isoform 1) Isoform 2is expressed in ovary, uterus, mammary glands, liver, lung, spleen, kidney, heart, bladder, intestine, skeletal muscle and brain. Ref.1 Ref.2
Induction: Down-regulated by oncogenes (isoform 1) Isoform 2is down-regulated by beta estradiol in mammary gland (at mRNA level). Isoform 2is up-regulated by beta estradiol in mammary glands (at protein level). Up-regulated in lactating mammary glands and mammary tumors (at protein level). Ref.1 Ref.2
Post-translational modification: Phosphorylated
By similarity.
Sequence similarities: Belongs to the CCDC80 family.
Sequence caution: The sequence AAF35351.1 differs from that shown. Reason: Frameshift at several positions.
Research Articles on CCDC80
Similar Products
Product Notes
The CCDC80 ccdc80 (Catalog #AAA2010837) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Coiled Coil Domain Containing Protein 80 (CCDC80) can be used in a range of immunoassay formats including, but not limited to, Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). Researchers should empirically determine the suitability of the CCDC80 ccdc80 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Coiled Coil Domain Containing Protein 80 (CCDC80), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
