RBM3 cdna clone
RBM3
Synonyms
RBM3; IS1-RNPL; RNPL; RBM3 cdna clone
Form/Format
Lyophilized
Sequence
Nucleotide Sequence: ATGTCCTCTGAAGAAGGAAAGCTCTTCGTGGGAGGGCTCAACTTTAACACCGACGAGCAGGCACTGGAAGACCACTTCAGCAGTTTCGGACCTATCTCTGAGGTGGTCGTTGTCAAGGACCGGGAGACTCAGCGGTCCAGGGGTTTTGGTTTCATCACCTTCACCAACCCAGAGCATGCTTCAGTTGCCATGAGAGCCATGAACGGAGAGTCTCTGGATGGTCGTCAGATCCGTGTGGATCATGCAGGCAAGTCTGCTCGGGGAACCAGAGGAGGTGGCTTTGGGGCCCATGGGCGTGGTCGCAGCTACTCTAGAGGTGGTGGGGACCAGGGCTATGGGAGTGGCAGGTATTATGACAGTCGACCTGGAGGGTATGGATATGGATATGGACGTTCCAGAGACTATAATGGCAGAAACCAGGGTGGTTATGACCGCTACTCAGGAGGAAATTACAGAGACAATTATGACAACTGA
Translation Sequence: MSSEEGKLFV GGLNFNTDEQ ALEDHFSSFG PISEVVVVKD RETQRSRGFG FITFTNPEHA SVAMRAMNGE SLDGRQIRVD HAGKSARGTR GGGFGAHGRG RSYSRGGGDQ GYGSGRYYDS RPGGYGYGYG RSRDYNGRNQ GGYDRYSGGN YRDNYDN
Translation Sequence: MSSEEGKLFV GGLNFNTDEQ ALEDHFSSFG PISEVVVVKD RETQRSRGFG FITFTNPEHA SVAMRAMNGE SLDGRQIRVD HAGKSARGTR GGGFGAHGRG RSYSRGGGDQ GYGSGRYYDS RPGGYGYGYG RSRDYNGRNQ GGYDRYSGGN YRDNYDN
Sequence Length
157
Species
Human
Chromosome Location
Xp11.2
OMIM Reference Number
300027
cDNA Size
474bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
Preparation and Storage
Store the plasmid at -20 degree C.
Related Product Information for RBM3 cdna clone
RBM3 is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria.
Product Categories/Family for RBM3 cdna clone
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
RNA-binding protein 3
UniProt Protein Name
RNA-binding protein 3
Protein Family
UniProt Gene Name
RBM3
UniProt Synonym Gene Names
RNPL
UniProt Entry Name
RBM3_HUMAN
Uniprot Description
RBM3: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation.
Protein type: Ribosomal; Translation; RNA-binding; RNA processing
Chromosomal Location of Human Ortholog: Xp11.2
Cellular Component: cytoplasm; dendrite; nucleus; large ribosomal subunit
Molecular Function: protein binding; RNA binding; nucleotide binding; ribosomal large subunit binding
Biological Process: RNA processing; regulation of translation; miRNA-mediated gene silencing, production of miRNAs; positive regulation of translation; translation; response to cold
Similar Products
Product Notes
The RBM3 rbm3 (Catalog #AAA200944) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGTCCTCTG AAGAAGGAAA GCTCTTCGTG GGAGGGCTCA ACTTTAACAC CGACGAGCAG GCACTGGAAG ACCACTTCAG CAGTTTCGGA CCTATCTCTG AGGTGGTCGT TGTCAAGGAC CGGGAGACTC AGCGGTCCAG GGGTTTTGGT TTCATCACCT TCACCAACCC AGAGCATGCT TCAGTTGCCA TGAGAGCCAT GAACGGAGAG TCTCTGGATG GTCGTCAGAT CCGTGTGGAT CATGCAGGCA AGTCTGCTCG GGGAACCAGA GGAGGTGGCT TTGGGGCCCA TGGGCGTGGT CGCAGCTACT CTAGAGGTGG TGGGGACCAG GGCTATGGGA GTGGCAGGTA TTATGACAGT CGACCTGGAG GGTATGGATA TGGATATGGA CGTTCCAGAG ACTATAATGG CAGAAACCAG GGTGGTTATG ACCGCTACTC AGGAGGAAAT TACAGAGACA ATTATGACAA CTGA Translat ion Sequence: MSSEEGKLFV GGLNFNTDEQ ALEDHFSSFG PISEVVVVKD RETQRSRGFG FITFTNPEHA SVAMRAMNGE SLDGRQIRVD HAGKSARGTR GGGFGAHGRG RSYSRGGGDQ GYGSGRYYDS RPGGYGYGYG RSRDYNGRNQ GGYDRYSGGN YRDNYDN. It is sometimes possible for the material contained within the vial of "RBM3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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