Diamine Oxidase (DAO) Recombinant Protein | DAO recombinant protein
Recombinant Diamine Oxidase (DAO)
MGHHHHHHSGS-GCDDRCLTFT DVAPRGVASG QRRSWFIVQR YVEGYFLHPT GLEILLDHGS TDVQDWRVEQ LWYNGKFYNN PEELARKYAV GEVDTVVLED PLPNGTEKPP LFSSYKPRGE FHTPVNVAGP HVVQPSGPRY KLEGNTVLYG GWSFSYRLRS SSG
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
NCBI Description
binds amiloride and some of its derivatives; may form an epithelial-specific Na+ channel [RGD, Feb 2006]
Uniprot Description
ABP1: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Belongs to the copper/topaquinone oxidase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tryptophan; Oxidoreductase; EC 1.4.3.22; Secreted; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - histidine; Secreted, signal peptide
Cellular Component: extracellular space; tight junction; plasma membrane
Molecular Function: amine oxidase activity; heparin binding; protein homodimerization activity; copper ion binding; zinc ion binding; protein complex binding; receptor activity; drug binding; cation channel activity; calcium ion binding; quinone binding
Biological Process: response to drug; response to antibiotic; amine metabolic process; cation transport