Testing Data
(Detection of HO-2 in rat brain lysates at 1ug/ml.)
Rabbit Heme Oxygenase-2 (HO-2) Polyclonal Antibody | anti-HO-2 antibody
Heme Oxygenase 2 (HO-2) Polyclonal Antibody
Gene Names
Hmox2; Ho-2
Applications
Immunoblot, Western Blot, Immunohistochemistry
Synonyms
Heme Oxygenase-2 (HO-2); Polyclonal Antibody; Heme Oxygenase 2 (HO-2) Polyclonal Antibody; anti-HO-2 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
This antibody recognizes human, mouse, and rat HO-2.
Form/Format
100ug (1mg/ml) Protein A-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Sequence Length
315
Applicable Applications for anti-HO-2 antibody
Immunoblot, Immunohistochemistry (IHC)
Application Notes
Immunoblot: 1ug/ml
IHC: 1ug/ml
Dilute in PBS or medium that is identical to that used in the assay system.
IHC: 1ug/ml
Dilute in PBS or medium that is identical to that used in the assay system.
Immunogen
Full-length native rat HO-2 purified from testes.
Preparation and Storage
This antibody is stable for at least one (1) year at-20 degree C.
Testing Data
(Detection of HO-2 in rat brain lysates at 1ug/ml.)
Testing Data
(Detection of HO-2 in rat brain lysates at 1ug/ml.)
Testing Data
(Detection of HO-2 in rat spinal cord at 1ug/ml. )
Testing Data
(Detection of HO-2 in rat spinal cord at 1ug/ml. )
Related Product Information for anti-HO-2 antibody
Heme oxygenase (HO) catalyzes the degradation of heme at the alpha-methene bridge to form biliverdin. Three isoforms of heme oxygenase are known. Heme oxygenase 1 (HO-1) is an inducible isoform in response to stress such as oxidative stress, hypoxia, heavy metals, cytokines, etc. Heme oxygenase 2 (HO-2) is a constitutive isoform that is expressed under homeostatic conditions. Both HO-1 and HO-2 are ubiquitously expressed and catalytically active. HO-1 is encoded by the HMOX1 gene and HO-2 by HMOX2. A third heme oxygenase (HO-3) is not catalytically active, but is thought to work in oxygen sensing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,762 Da
NCBI Official Full Name
heme oxygenase 2
NCBI Official Synonym Full Names
heme oxygenase 2
NCBI Official Symbol
Hmox2
NCBI Official Synonym Symbols
Ho-2
NCBI Protein Information
heme oxygenase 2
UniProt Protein Name
Heme oxygenase 2
UniProt Gene Name
Hmox2
UniProt Synonym Gene Names
HO-2
NCBI Description
catalyzes the conversion of heme to biliverdin; involved in cellular response to oxidative stress [RGD, Feb 2006]
Uniprot Description
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Research Articles on HO-2
Similar Products
Product Notes
The HO-2 hmox2 (Catalog #AAA191314) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Heme Oxygenase-2 (HO-2) can be used in a range of immunoassay formats including, but not limited to, Immunoblot, Immunohistochemistry (IHC). Immunoblot: 1ug/ml IHC: 1ug/ml Dilute in PBS or medium that is identical to that used in the assay system. Researchers should empirically determine the suitability of the HO-2 hmox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Heme Oxygenase-2 (HO-2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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