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Mouse TATA - Binding Protein Monoclonal Antibody | anti-Tbp antibody

TATA-Binding Protein Monoclonal Antibody

Gene Names
Tbp; CG9874; DmelCG9874; dTbp; dTBP; dTFIID; RBP; TBP; TBP38; TfIID; TFIID; TFIIDtau
Applications
Western Blot, Immunoprecipitation
Synonyms
TATA - Binding Protein; Monoclonal Antibody; TATA-Binding Protein Monoclonal Antibody; Anti-TATA - Binding Protein; TATA Binding Protein (TBP); anti-Tbp antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
Anti-TATA - Binding Protein [Murine MAb recognizes epitope within aa residues 1-20 of human, mouse and rat TBP.]
This antibody recognizes an epitope within amino acid residues 1-20 of human, mouse and rat TBP. It does not react with TBP from Drosophila, yeast, silk worm, or Xenopus. The specific epitope for this antibody is accessible when the C-terminal domain of TBP is removed or when TBP is complexed with DNA.
Form/Format
200 ug Protein G purified antibody in PBS, pH 7.4.
Sequence Length
353
Applicable Applications for anti-Tbp antibody
Western Blot, Immunoprecipitation
Application Notes
This antibody may be used in Western Blot and electrophoretic mobility (gel shift) assays to detect mammalian TBP. It may also be used to immunoprecipitate a truncated TBP molecule containing only the N-terminal domain.
Antigen
N-terminal domain of the human TATA-binding protein (TBP).
Preservatives
None. Available on request
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles
Product Categories/Family for anti-Tbp antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,451 Da
NCBI Official Full Name
TATA binding protein
NCBI Official Synonym Full Names
TATA binding protein
NCBI Official Symbol
Tbp
NCBI Official Synonym Symbols
CG9874; DmelCG9874; dTbp; dTBP; dTFIID; RBP; TBP; TBP38; TfIID; TFIID; TFIIDtau
NCBI Protein Information
CG9874 gene product from transcript CG9874-RA; TATA binding protein; CG9874-PA; Tbp-PA; TATA box binding protein; 42kDa polypeptide; TATA box-binding protein; TATA-binding protein; TATA-box binding protein
UniProt Protein Name
TATA-box-binding protein
Protein Family
UniProt Gene Name
Tbp
UniProt Synonym Gene Names
BTF1; TFIID
UniProt Entry Name
TBP_DROME

Uniprot Description

Function: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Ref.1 Ref.2 Ref.8

Subunit structure: Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (Tafs). Binds DNA as monomer. Interacts with TFIIA-L heterotrimer. Interacts with Taf1, Taf2, Taf5 and Taf12. Ref.8 Ref.9 Ref.10 Ref.11 Ref.12

Subcellular location: Nucleus.

Sequence similarities: Belongs to the TBP family.

Research Articles on Tbp

Similar Products

Product Notes

The Tbp tbp (Catalog #AAA190431) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TATA - Binding Protein can be used in a range of immunoassay formats including, but not limited to, Western Blot, Immunoprecipitation. This antibody may be used in Western Blot and electrophoretic mobility (gel shift) assays to detect mammalian TBP. It may also be used to immunoprecipitate a truncated TBP molecule containing only the N-terminal domain. Researchers should empirically determine the suitability of the Tbp tbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TATA - Binding Protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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