Mass Cytometry (MC)
(Mass cytometry of brain tumor cells with anti-drebrin (DBN-N-03) 152Sm. Gated on singlets.)
Mouse anti-Human Drebrin Monoclonal Antibody | anti-DBN1 antibody
Anti-Drebrin Purified
Mass Cytometry (MC)
(Mass cytometry of brain tumor cells with anti-drebrin (DBN-N-03) 152Sm. Gated on singlets.)
Mass Cytometry (MC)
(Mass cytometry of brain tumor cells with anti-drebrin (DBN-N-03) 152Sm. Gated on singlets.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
DBN1: a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. Expressed in brain neurons, heart, placenta, skeletal muscle, kidney and pancreas. Two alternatively spliced isoforms have been described.
Protein type: Motility/polarity/chemotaxis; Actin-binding; Cytoskeletal
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: cytoplasm; dendrite; plasma membrane; gap junction; actomyosin; cell cortex; actin cytoskeleton
Molecular Function: protein binding; actin binding; profilin binding
Biological Process: maintenance of cellular protein localization; regulation of dendrite development; actin filament organization; regulation of neuronal synaptic plasticity
Research Articles on DBN1
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Product Notes
The DBN1 dbn1 (Catalog #AAA1800536) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Drebrin Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Drebrin can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB), MC (CyTOF). FC/FACS: QC tested. Researchers should empirically determine the suitability of the DBN1 dbn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Drebrin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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