Human Latent-transforming growth factor beta-binding protein 1 (LTBP1) ELISA Kit | LTBP1 elisa kit

Human Latent-transforming growth factor beta-binding protein 1 (LTBP1) ELISA Kit

Cat. Num. AAA167380

• Reactivity: Human
• Synonyms: Latent-transforming growth factor beta-binding protein 1 (LTBP1); Human Latent-transforming growth factor beta-binding protein 1 (LTBP1) ELISA Kit; LTBP1 elisa kit

• Reactivity: Human
• Sequence Length: 1712

• Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 10ng/L - 3000ng/L
• Sensitivity: 5.41ng/L
• Intra-Assay: CV<8%
• Inter-Assay: CV<10%
• Preparation and Storage: Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for LTBP1 elisa kit

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Latent-transforming Growth Factor Beta-binding Protein 1 (also known as LTBP1) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human LTBP1 antibody. LTBP1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human LTBP1 Antibody is added and binds to LTBP1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated LTBP1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human LTBP1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

• NCBI GI #: 11024664
• NCBI GeneID: 59107
• NCBI Accession #: NP_067598.1
• NCBI GenBank Nucleotide #: NM_021587.1
• UniProt Accession #: Q00918
• Molecular Weight: 186,599 Da
• NCBI Official Full Name: latent-transforming growth factor beta-binding protein 1
• NCBI Official Synonym Full Names: latent transforming growth factor beta binding protein 1
• NCBI Official Symbol: Ltbp1
• NCBI Protein Information: latent-transforming growth factor beta-binding protein 1
• UniProt Protein Name: Latent-transforming growth factor beta-binding protein 1
• Protein Family: Latent-transforming growth factor beta-binding protein
• UniProt Gene Name: Ltbp1
• UniProt Synonym Gene Names: LTBP-1; TGF-beta-1-BP-1

NCBI Description

large subunit component of masking protein; neutralizes the activity of TGF-beta 1 [RGD, Feb 2006]

Uniprot Description

May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM).