Western Blot (WB)
(Western blot analysis of ZC3H12D in THP-1 cell lysate with ZC3H12D antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
ZC3H12D blocking peptide
ZC3H12D Peptide
Western Blot (WB)
(Western blot analysis of ZC3H12D in THP-1 cell lysate with ZC3H12D antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of ZC3H12D in THP-1 cell lysate with ZC3H12D antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
NCBI and Uniprot Product Information
Uniprot Description
ZC3H12D: May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation. A chromosomal aberration involving ZC3H12D may be the cause of the transformation of follicular lymphoma (FL) to diffuse large B-cell lymphoma (DLBCL). Translocation t(2;6)(p12;q25) with IGK. Resulting protein may not be expressed. Belongs to the ZC3H12 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.-.-; Hydrolase
Chromosomal Location of Human Ortholog: 6q25.1
Cellular Component: cytoplasm; nucleus
Molecular Function: endonuclease activity; metal ion binding
Biological Process: negative regulation of cell growth
Research Articles on ZC3H12D
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Product Notes
The ZC3H12D zc3h12d (Catalog #AAA152244) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ZC3H12D can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). ZC3H12D peptide is used for blocking the activity of ZC3H12D antibody. Researchers should empirically determine the suitability of the ZC3H12D zc3h12d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZC3H12D, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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