Lysine-specific demethylase 6B (Kdm6b) Recombinant Protein | Kdm6b recombinant protein
Recombinant Mouse Lysine-specific demethylase 6B (Kdm6b) , partial
Gene Names
Kdm6b; Jmjd3; BC038313; mKIAA0346; 1700064E03Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Lysine-specific demethylase 6B (Kdm6b); Recombinant Mouse Lysine-specific demethylase 6B (Kdm6b); partial; Kdm6b recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1041-1641. Partial.
Sequence
KVKTPTAPAPPPAPAPAAQPTPPSAPVPGKKTREEAPGPPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVMRASKNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEERESEDEESEEPDSTTGTSPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLEQYRTEELAQAYDAFTLAPASTSR
Sequence Length
1641
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
176,355 Da
NCBI Official Full Name
lysine-specific demethylase 6B
NCBI Official Synonym Full Names
KDM1 lysine (K)-specific demethylase 6B
NCBI Official Symbol
Kdm6b
NCBI Official Synonym Symbols
Jmjd3; BC038313; mKIAA0346; 1700064E03Rik
NCBI Protein Information
lysine-specific demethylase 6B
UniProt Protein Name
Lysine-specific demethylase 6B
Protein Family
UniProt Gene Name
Kdm6b
UniProt Synonym Gene Names
Jmjd3; Kiaa0346
Uniprot Description
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (PubMed:21095589).
Research Articles on Kdm6b
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Product Notes
The Kdm6b kdm6b (Catalog #AAA1476197) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1041-1641. Partial. The amino acid sequence is listed below: KVKTPTAPAP PPAPAPAAQP TPPSAPVPGK KTREEAPGPP GVSRADMLKL RSLSEGPPKE LKIRLIKVES GDKETFIASE VEERRLRMAD LTISHCAADV MRASKNAKVK GKFRESYLSP AQSVKPKINT EEKLPREKLN PPTPSIYLES KRDAFSPVLL QFCTDPRNPI TVIRGLAGSL RLNLGLFSTK TLVEASGEHT VEVRTQVQQP SDENWDLTGT RQIWPCESSR SHTTIAKYAQ YQASSFQESL QEERESEDEE SEEPDSTTGT SPSSAPDPKN HHIIKFGTNI DLSDAKRWKP QLQELLKLPA FMRVTSTGNM LSHVGHTILG MNTVQLYMKV PGSRTPGHQE NNNFCSVNIN IGPGDCEWFA VHEHYWETIS AFCDRHGVDY LTGSWWPILD DLYASNIPVY RFVQRPGDLV WINAGTVHWV QATGWCNNIA WNVGPLTAYQ YQLALERYEW NEVKNVKSIV PMIHVSWNVA RTVKISDPDL FKMIKFCLLQ SMKHCQVQRE SLVRAGKKIA YQGRVKDEPA YYCNECDVEV FNILFVTSEN GSRNTYLVHC EGCARRRSAG LQGVVVLEQY RTEELAQAYD AFTLAPASTS R . It is sometimes possible for the material contained within the vial of "Lysine-specific demethylase 6B (Kdm6b), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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