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Histone-lysine N-methyltransferase SUV39H2 (suv39h2) Recombinant Protein | suv39h2 recombinant protein

Recombinant Xenopus tropicalis Histone-lysine N-methyltransferase SUV39H2 (suv39h2)

Gene Names
suv39h2; kmt1b
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Histone-lysine N-methyltransferase SUV39H2 (suv39h2); Recombinant Xenopus tropicalis Histone-lysine N-methyltransferase SUV39H2 (suv39h2); suv39h2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-406, Full length protein
Sequence
MAAARGAWCVPCLASIETLQELCRKEMLICTNIGITRKNLNNYEVEYLCDYRIEKGVEKFFVKWKGWPESCNTWEPTRNLKCPTLLKQFYSDLYNYFCALKPNKKGFLKNSIKSLDPSLSDYIVKKAKQRIALRRWEEELNRKKTHSGTLFVENTVDLEGPPMDFYYINDYKASPGVNTLGEAIVGCDCSDCFKGKCCPTEAGVLFAYNEHRQIKIPPGRPIYECNSRCKCGPDCPNRVVQKGPPYSLCIFRTDNGRGWGVKTLQKIKKNSFVMEYVGEVITSEEAERRGQQYDSRGITYLFDLDYEADEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDVRLPRIALFSTRNIKAGEELTFDYQMKGSGDFSTDSIDMSPAKKRVRIACKCGAATCRGYLN
Sequence Length
406
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,350 Da
NCBI Official Full Name
histone-lysine N-methyltransferase SUV39H2
NCBI Official Synonym Full Names
suppressor of variegation 3-9 homolog 2
NCBI Official Symbol
suv39h2
NCBI Official Synonym Symbols
kmt1b
NCBI Protein Information
histone-lysine N-methyltransferase SUV39H2
UniProt Protein Name
Histone-lysine N-methyltransferase SUV39H2
UniProt Gene Name
suv39h2
UniProt Synonym Gene Names
Su(var)3-9 homolog 2

Uniprot Description

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes ().

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Product Notes

The suv39h2 suv39h2 (Catalog #AAA1468055) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-406, Full length protein. The amino acid sequence is listed below: MAAARGAWCV PCLASIETLQ ELCRKEMLIC TNIGITRKNL NNYEVEYLCD YRIEKGVEKF FVKWKGWPES CNTWEPTRNL KCPTLLKQFY SDLYNYFCAL KPNKKGFLKN SIKSLDPSLS DYIVKKAKQR IALRRWEEEL NRKKTHSGTL FVENTVDLEG PPMDFYYIND YKASPGVNTL GEAIVGCDCS DCFKGKCCPT EAGVLFAYNE HRQIKIPPGR PIYECNSRCK CGPDCPNRVV QKGPPYSLCI FRTDNGRGWG VKTLQKIKKN SFVMEYVGEV ITSEEAERRG QQYDSRGITY LFDLDYEADE FTVDAARYGN VSHFVNHSCD PNLQVFNVFI DNLDVRLPRI ALFSTRNIKA GEELTFDYQM KGSGDFSTDS IDMSPAKKRV RIACKCGAAT CRGYLN. It is sometimes possible for the material contained within the vial of "Histone-lysine N-methyltransferase SUV39H2 (suv39h2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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