Lissencephaly-1 homolog (PAFAH1B1) Recombinant Protein | PAFAH1B1 recombinant protein
Recombinant Chicken Lissencephaly-1 homolog (PAFAH1B1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Lissencephaly-1 homolog (PAFAH1B1); Recombinant Chicken Lissencephaly-1 homolog (PAFAH1B1); PAFAH1B1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-410, Full length protein
Sequence
VLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHTGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSTISEATGSETKKSGKPGPFLLSGSRDKTIKMWDISTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDFKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR
Sequence Length
409
Species
Chicken
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for PAFAH1B1 recombinant protein
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,664 Da
NCBI Official Full Name
lissencephaly-1 homolog
NCBI Official Synonym Full Names
platelet activating factor acetylhydrolase 1b regulatory subunit 1
NCBI Official Symbol
PAFAH1B1
NCBI Protein Information
lissencephaly-1 homolog
UniProt Protein Name
Lissencephaly-1 homolog
Protein Family
UniProt Gene Name
PAFAH1B1
Uniprot Description
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
Research Articles on PAFAH1B1
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Product Notes
The PAFAH1B1 pafah1b1 (Catalog #AAA1456863) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-410, Full length protein. The amino acid sequence is listed below: VLSQRQRDEL NRAIADYLRS NGYEEAYSVF KKEAELDVNE ELDKKYAGLL EKKWTSVIRL QKKVMELESK LNEAKEEFTS GGPLGQKRDP KEWIPRPPEK YALSGHRSPV TRVIFHPVFS VMVSASEDAT IKVWDYETGD FERTLKGHTD SVQDISFDHT GKLLASCSAD MTIKLWDFQG FECIRTMHGH DHNVSSVAIM PNGDHIVSAS RDKTIKMWEV QTGYCVKTFT GHREWVRMVR PNQDGTLIAS CSNDQTVRVW VVATKECKAE LREHEHVVEC ISWAPESSYS TISEATGSET KKSGKPGPFL LSGSRDKTIK MWDISTGMCL MTLVGHDNWV RGVLFHSGGK FILSCADDKT LRVWDFKNKR CMKTLNAHEH FVTSLDFHKT APYVVTGSVD QTVKVWECR. It is sometimes possible for the material contained within the vial of "Lissencephaly-1 homolog (PAFAH1B1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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