Constitutive photomorphogenesis protein 10 (COP10) Recombinant Protein | COP10 recombinant protein

Recombinant Arabidopsis thaliana Constitutive photomorphogenesis protein 10 (COP10)

Cat. Num. AAA1455984

• Gene Names: FUS9; CIN4; CONSTITUTIVE PHOTOMORPHOGENIC 10; COP10; CYTOKININ-INSENSITIVE 4; E2 UBIQUITIN-CONJUGATING ENZYME; EMB144; EMBRYO DEFECTIVE 144; FUSCA 9
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Constitutive photomorphogenesis protein 10 (COP10); Recombinant Arabidopsis thaliana Constitutive photomorphogenesis protein 10 (COP10); COP10 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-182, Full length protein
• Sequence: MMTPGGSGRLRPLPTAMYAGYSGTASSWVAKTSVSASGKRIQREMAELNIDPPPDCSAGPKGDNLYHWIATIIGPSGTPYEGGIFFLDIIFPSDYPFKPPKLVFKTRIYHCNVDTAGDLSVNILRDSWSPALTITKVLQAIRSIFLKPEPYSPALPVIARLYLTDREKHDEVAKEWTLRFAK
• Sequence Length: 182

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 22331064
• NCBI GeneID: 820557
• NCBI Accession #: NP_566459.2
• NCBI GenBank Nucleotide #: NM_112201.5
• UniProt Accession #: Q9LJD7
• Molecular Weight: 20,130 Da
• NCBI Official Full Name: Ubiquitin-conjugating enzyme family protein
• NCBI Official Symbol: FUS9
• NCBI Official Synonym Symbols: CIN4; CONSTITUTIVE PHOTOMORPHOGENIC 10; COP10; CYTOKININ-INSENSITIVE 4; E2 UBIQUITIN-CONJUGATING ENZYME; EMB144; EMBRYO DEFECTIVE 144; FUSCA 9
• NCBI Protein Information: Ubiquitin-conjugating enzyme family protein
• UniProt Protein Name: Constitutive photomorphogenesis protein 10
• Protein Family: Constitutive photomorphogenesis protein
• UniProt Gene Name: COP10

NCBI Description

Encodes a protein similar to ubiquitin-conjugating enzyme (E2) variant proteins (UEV); lacks catalytic cysteine residue found in ubiquitin-conjugating enzyme E2. Represses photomorphogenesis and induces skotomorphogenesis in the dark.

Uniprot Description

Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Although strongly related to ubiquitin-conjugating enzyme, it has no catalytic activity by itself due to the absence of the conserved Cys active site at position 120. It can however enhance the activity of E2 conjugating enzymes.