Small Nuclear Ribonucleoprotein Recombinant Protein | SNRPG recombinant protein
Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide G
Sterile Filtered colorless solution.
Introduction: Small nuclear ribonucleoprotein polypeptide G (SNRPG) is a member of the snRNP Sm proteins family. There are at least 7 isoforms, B/B, E, F, G, D1, D2, and D3. This class of common proteins has a vital role in the biogenesis of the snRNPs. The human Sm G genes are mapped to chromosomes 2. Furthermore, these proteins represent the major targets for the supposed anti-Sm auto-antibodies which are for SLE (systemic lupus erythematosus). One class of these autoantibodies reacts specifically with native Sm E-F-G complexes.
NCBI and Uniprot Product Information
Uniprot Description
snRNP G: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
Protein type: Spliceosome; RNA splicing; RNA-binding
Chromosomal Location of Human Ortholog: 2p13.3
Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; spliceosome; snRNP U1; cytosol; U12-dependent spliceosome
Molecular Function: protein binding
Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; spliceosomal snRNP biogenesis; RNA splicing; spliceosome assembly; histone mRNA metabolic process; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription
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Product Notes
The SNRPG snrpg (Catalog #AAA145290) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MSKAHPPELK KFMDKKLSLK LNGGRHVQGI LRGFDPFMNL VIDECVEMAT SGQQNNIGMV VIRGNSIIML EALERV.. It is sometimes possible for the material contained within the vial of "Small Nuclear Ribonucleoprotein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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