Ras Homolog Gene Family Member D Recombinant Protein | RHOD recombinant protein

Recombinant Human Ras Homolog Gene Family Member D

Cat. Num. AAA144556

• Gene Names: RHOD; Rho; ARHD; RHOM; RHOHP1
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Synonyms: Ras Homolog Gene Family Member D; Recombinant Human Ras Homolog Gene Family Member D; RHOD Human; Ras Homolog Gene Family Member D Human Recombinant; Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1; RHOD; ARHD; Rho; RHOM; RHOD recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 90.0% as determined by SDS-PAGE.
• Form/Format: The RHOD solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 50% glycerol, 200mM NaCl, 2mM EDTA and 0.1mM PMSF.; Sterile Filtered colorless solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MVKVVLVGDG GCGKTSLLMV FADGAFPESY TPTVFERYMV NLQVKGKPVH LHIWDTAGQD DYDRLRPLFY PDASVLLLCF DVTSPNSFDN IFNRWYPEVN HFCKKVPIIV VGCKTDLRKD KSLVNKLRRN GLEPVTYHRG QEMARSVGAV AYLECSARLHDNVHAVFQEA AEVALSSRGR NFWRRITQGF C.
• Sequence Length: 210

Related Product Information for RHOD recombinant protein

Description: RHOD produced in E Coli is a single, non-glycosylated polypeptide chain containing 211 amino acids (18-207 a.a.) and having a molecular mass of 23.8kDa.RHOD is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Rho-related GTP-binding protein (RhoD) is a member of the small GTPase superfamily. The small GTPase Rho D promotes the rearrangement of the actin cytoskeleton and cell surface and also regulates endosome motility and distribution.

Product Categories/Family for RHOD recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Member RAS Oncogene Family

NCBI and Uniprot Product Information

• NCBI GI #: 7656900
• NCBI GeneID: 29984
• NCBI Accession #: NP_055393.1
• NCBI GenBank Nucleotide #: NM_014578.3
• UniProt Accession #: O00212
• Molecular Weight: 23,413 Da
• NCBI Official Full Name: rho-related GTP-binding protein RhoD isoform 1
• NCBI Official Synonym Full Names: ras homolog family member D
• NCBI Official Symbol: RHOD
• NCBI Official Synonym Symbols: Rho; ARHD; RHOM; RHOHP1
• NCBI Protein Information: rho-related GTP-binding protein RhoD; Rho-related protein HP1; ras homolog D; ras homolog gene family, member A; ras homolog gene family, member D
• UniProt Protein Name: Rho-related GTP-binding protein RhoD
• Protein Family: Rho-related GTP-binding protein
• UniProt Gene Name: RHOD
• UniProt Synonym Gene Names: ARHD; RhoHP1
• UniProt Entry Name: RHOD_HUMAN

NCBI Description

Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Uniprot Description

RHOD: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein, monomeric; G protein; Motility/polarity/chemotaxis; G protein, monomeric, Rho

Chromosomal Location of Human Ortholog: 11q14.3

Cellular Component: early endosome; plasma membrane; cytosol

Molecular Function: GTPase activity; GTP binding; protein kinase binding

Biological Process: focal adhesion formation; lamellipodium biogenesis; actin filament bundle formation; regulation of small GTPase mediated signal transduction; positive regulation of cell adhesion; metabolic process; small GTPase mediated signal transduction; regulation of focal adhesion formation; Rho protein signal transduction; positive regulation of cell migration; protein targeting