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Eukaryotic Translation Initiation Factor 1A Y-linked Recombinant Protein | EIF1AY recombinant protein

Recombinant Human Eukaryotic Translation Initiation Factor 1A Y-linked

Gene Names
EIF1AY; eIF-4C
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
Eukaryotic Translation Initiation Factor 1A Y-linked; Recombinant Human Eukaryotic Translation Initiation Factor 1A Y-linked; EIF1AY Human; Eukaryotic Translation Initiation Factor 1A Y-linked Recombinant Human; Eukaryotic translation initiation factor 1A Y chromosome; Eukaryotic translation initiation factor 4C; eIF-4C; eIF-1A Y isoform; EIF1AY recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
The EIF1AY protein solution (0.5mg/1ml) is formulated in 20 mM Tris-HCl buffer (pH8.0), 0.1M NaCl, 1mM DTT and 20% glycerol.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MSSMNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI RTIELDGKTI KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDVTDQESFN NVKQWLQEID RYASENVNKL LVGNKCDLTT KKVVDYTTAK EFADSLGIPF LETSAKNATN  VEQSFMTMAA EIKKRMGPGA TAGGAEKSNV KIQSTPVKQS GGGCC
Sequence Length
127
Related Product Information for EIF1AY recombinant protein
Description: EIF1AY produced in E Coli is a single, non-glycosylated polypeptide chain containing 167 amino acids (1-144.a.a) and having a molecular mass of 18.8kDa. EIF1AY is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: EIF1AY is comparable to eukaryotic translation initiation factor 1A (EIF1A). EIF1AY protein is essential for highest rate of protein biosynthesis. EIF1AY increases ribosome dissociation into subunits and is obligatory for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,442 Da
NCBI Official Full Name
eukaryotic translation initiation factor 1A, Y-chromosomal isoform 2
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 1A, Y-linked
NCBI Official Symbol
EIF1AY
NCBI Official Synonym Symbols
eIF-4C
NCBI Protein Information
eukaryotic translation initiation factor 1A, Y-chromosomal; eIF-1A Y isoform; eukaryotic translation initiation factor 1A, Y chromosome; eukaryotic translation initiation factor 4C
UniProt Protein Name
Eukaryotic translation initiation factor 1A, Y-chromosomal
UniProt Gene Name
EIF1AY
UniProt Synonym Gene Names
eIF-1A Y isoform; eIF-4C
UniProt Entry Name
IF1AY_HUMAN

NCBI Description

This gene is located on the non-recombining region of the Y chromosome. It encodes a protein related to eukaryotic translation initiation factor 1A (EIF1A), which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

EIF1AY: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. Belongs to the eIF-1A family.

Protein type: Translation; Translation initiation

Chromosomal Location of Human Ortholog: Yq11.223

Molecular Function: protein binding; translation initiation factor activity

Biological Process: translational initiation

Research Articles on EIF1AY

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Product Notes

The EIF1AY eif1ay (Catalog #AAA144341) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MSSMNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI RTIELDGKTI KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDVTDQESFN NVKQWLQEID RYASENVNKL LVGNKCDLTT KKVVDYTTAK EFADSLGIPF LETSAKNATN   VEQSFMTMAA EIKKRMGPGA TAGGAEKSNV KIQSTPVKQS GGGCC. It is sometimes possible for the material contained within the vial of "Eukaryotic Translation Initiation Factor 1A Y-linked, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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