Signal Recognition Particle Recombinant Protein | SRP14 recombinant protein
Recombinant Human Signal Recognition Particle 14kDa
Gene Names
SRP14; ALURBP
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Signal Recognition Particle; Recombinant Human Signal Recognition Particle 14kDa; SRP14 Human; Signal Recognition Particle 14kDa Human Recombinant; Signal recognition particle 14 kDa protein; SRP14; 18 kDa Alu RNA-binding protein; ALURBP; MGC14326; SRP14 recombinant protein
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
The SRP14 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMVLLES EQFLTELTRL FQKCRTSGSV YITLKKYDGR TKPIPKKGTV EGFEPADNKC LLRATDGKKK ISTVVSSKEV NKFQMAYSNL LRANMDGLKK RDKKNKTKKT KAAAAAAAAA PAAAATAATT AATTAATAAQ
Sequence Length
136
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for SRP14 recombinant protein
Description: SRP14 Human Recombinant fused with a 24 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 160 amino acids (1-136 a.a.) and having a molecular mass of 17.1kDa. The SRP14 is purified by proprietary chromatographic techniques.
Introduction: SRP14 is a ribonucleoprotein complex which mediates the directing of proteins to the endoplasmic reticulum. The œAlu domain of SRP is comprised of the heterodimer of the SRP9 and SRP14 proteins that are bound to the 5' and 3' terminal sequences of SRP RNA. SRP9/14 binding may be critical to the transcription, maturation, nucleolus localization and transport of SRP RNA.
Introduction: SRP14 is a ribonucleoprotein complex which mediates the directing of proteins to the endoplasmic reticulum. The œAlu domain of SRP is comprised of the heterodimer of the SRP9 and SRP14 proteins that are bound to the 5' and 3' terminal sequences of SRP RNA. SRP9/14 binding may be critical to the transcription, maturation, nucleolus localization and transport of SRP RNA.
Product Categories/Family for SRP14 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,570 Da
NCBI Official Full Name
signal recognition particle 14 kDa protein
NCBI Official Synonym Full Names
signal recognition particle 14kDa (homologous Alu RNA binding protein)
NCBI Official Symbol
SRP14
NCBI Official Synonym Symbols
ALURBP
NCBI Protein Information
signal recognition particle 14 kDa protein; 18 kDa Alu RNA-binding protein
UniProt Protein Name
Signal recognition particle 14 kDa protein
Protein Family
UniProt Gene Name
SRP14
UniProt Synonym Gene Names
SRP14
UniProt Entry Name
SRP14_HUMAN
Uniprot Description
SRP14: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. Belongs to the SRP14 family.
Protein type: Translation; RNA-binding
Chromosomal Location of Human Ortholog: 15q22
Cellular Component: intercellular bridge; cytoplasm; signal recognition particle, endoplasmic reticulum targeting; nucleolus; cytosol; nucleus
Molecular Function: protein binding; RNA binding; endoplasmic reticulum signal peptide binding; 7S RNA binding
Biological Process: response to drug; protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; gene expression; cotranslational protein targeting to membrane
Research Articles on SRP14
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Product Notes
The SRP14 srp14 (Catalog #AAA144184) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSHMV LLES EQFLTELTRL FQKCRTSGSV YITLKKYDGR TKPIPKKGTV EGFEPADNKC LLRATDGKKK ISTVVSSKEV NKFQMAYSNL LRANMDGLKK RDKKNKTKKT KAAAAAAAAA PAAAATAATT AATTAATAAQ. It is sometimes possible for the material contained within the vial of "Signal Recognition Particle, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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