Protein Phosphatase 1D Recombinant Protein | PPM1D recombinant protein
Recombinant Human Protein Phosphatase 1D
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Protein Phosphatase 1D; Recombinant Human Protein Phosphatase 1D; PPM1D Human; Protein Phosphatase 1D Human Recombinant; Protein phosphatase 1D magnesium-dependent; delta isoform; PPM1D; PP2C-DELTA; WIP1; PPM1D recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
PPM1D protein solution (0.5mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MVAFFAVCDG HGGREAAQFA REHFWGFIKK QKGFTSSEPA KVCAAIRKGF LACHLAMWKK LAEWPKTMTG LPSTSGTTAS VVIIRGMKMY VAHVGDSGVV LGIQDDPKDD FVRAVEVTQD HKPELPKERE RIEGLGGSVM NKSGVNRVVW KRPRLTHNGP VRRSTVIDQI PFLAVARALG DLWSYDFFSG EFVVSPEPDT SVHTLDPQKH KYIILGSDGL WNMIPPQDAI SMCQDQEEKK YLMGEHGQSC AKMLVNRALG RWRQRMLRAD NTSAIVICI.
Sequence Length
605
Related Product Information for PPM1D recombinant protein
Introduction: Protein Phosphatase 1D (PPM1D) belongs to the PP2C family of Ser/Thr protein phosphatases whose members are negative regulators of cell stress response pathways. PPM1D is induced by tumor suppressor protein TP53/p53 in response to multiple environmental stresses. PPM1D is a negative regulator of the activity of p38 MAP kinase through which it reduces the phosphorylation of p53 and suppresses p53-mediated transcription and apoptosis. PPM1D is located in a chromosomal area which enlarges in breast cancer.
Description: PPM1D Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 299 amino acids (98-375a.a.) and having a molecular mass of 33.2kDa.PPM1D is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Description: PPM1D Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 299 amino acids (98-375a.a.) and having a molecular mass of 33.2kDa.PPM1D is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for PPM1D recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
66,709 Da
NCBI Official Full Name
Protein phosphatase 1D magnesium-dependent, delta isoform
UniProt Protein Name
Protein phosphatase 1D magnesium-dependent, delta isoform
Protein Family
UniProt Gene Name
PPM1D
UniProt Entry Name
Q8NEA7_HUMAN
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Product Notes
The PPM1D ppm1d (Catalog #AAA140637) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MVAFFAVCDG HGGREAAQFA REHFWGFIKK QKGFTSSEPA KVCAAIRKGF LACHLAMWKK LAEWPKTMTG LPSTSGTTAS VVIIRGMKMY VAHVGDSGVV LGIQDDPKDD FVRAVEVTQD HKPELPKERE RIEGLGGSVM NKSGVNRVVW KRPRLTHNGP VRRSTVIDQI PFLAVARALG DLWSYDFFSG EFVVSPEPDT SVHTLDPQKH KYIILGSDGL WNMIPPQDAI SMCQDQEEKK YLMGEHGQSC AKMLVNRALG RWRQRMLRAD NTSAIVICI. . It is sometimes possible for the material contained within the vial of "Protein Phosphatase 1D, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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