Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) Recombinant Protein | DYNC1I2 recombinant protein
Recombinant Human Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2)
Gene Names
DYNC1I2; IC2; DIC74; DNCI2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2); Recombinant Human Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2); DYNC1I2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-638, Full length protein
Sequence
SDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
Sequence Length
637
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70,485 Da
NCBI Official Full Name
cytoplasmic dynein 1 intermediate chain 2 isoform 1
NCBI Official Synonym Full Names
dynein cytoplasmic 1 intermediate chain 2
NCBI Official Symbol
DYNC1I2
NCBI Official Synonym Symbols
IC2; DIC74; DNCI2
NCBI Protein Information
cytoplasmic dynein 1 intermediate chain 2
UniProt Protein Name
Cytoplasmic dynein 1 intermediate chain 2
Protein Family
UniProt Gene Name
DYNC1I2
UniProt Synonym Gene Names
DNCI2; DNCIC2; DH IC-2
NCBI Description
This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Uniprot Description
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.
Research Articles on DYNC1I2
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Product Notes
The DYNC1I2 dync1i2 (Catalog #AAA1397191) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-638, Full length protein. The amino acid sequence is listed below: SDKSELKAEL ERKKQRLAQI REEKKRKEEE RKKKETDQKK EAVAPVQEES DLEKKRREAE ALLQSMGLTP ESPIVFSEYW VPPPMSPSSK SVSTPSEAGS QDSGDGAVGS RTLHWDTDPS VLQLHSDSDL GRGPIKLGMA KITQVDFPPR EIVTYTKETQ TPVMAQPKED EEEDDDVVAP KPPIEPEEEK TLKKDEENDS KAPPHELTEE EKQQILHSEE FLSFFDHSTR IVERALSEQI NIFFDYSGRD LEDKEGEIQA GAKLSLNRQF FDERWSKHRV VSCLDWSSQY PELLVASYNN NEDAPHEPDG VALVWNMKYK KTTPEYVFHC QSAVMSATFA KFHPNLVVGG TYSGQIVLWD NRSNKRTPVQ RTPLSAAAHT HPVYCVNVVG TQNAHNLISI STDGKICSWS LDMLSHPQDS MELVHKQSKA VAVTSMSFPV GDVNNFVVGS EEGSVYTACR HGSKAGISEM FEGHQGPITG IHCHAAVGAV DFSHLFVTSS FDWTVKLWTT KNNKPLYSFE DNADYVYDVM WSPTHPALFA CVDGMGRLDL WNLNNDTEVP TASISVEGNP ALNRVRWTHS GREIAVGDSE GQIVIYDVGE QIAVPRNDEW ARFGRTLAEI NANRADAEEE AATRIPA. It is sometimes possible for the material contained within the vial of "Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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