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Testing Data

Rabbit DYNC1I2 Polyclonal Antibody | anti-DYNC1I2 antibody

DYNC1I2 Antibody

Gene Names
DYNC1I2; IC2; DNCI2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunofluorescence
Purity
Antigen affinity purification
Synonyms
DYNC1I2; Polyclonal Antibody; DYNC1I2 Antibody; DNCI2; FLJ21089; FLJ90842; IC2; MGC104199; MGC111094; MGC9324; anti-DYNC1I2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Sequence Length
612
Applicable Applications for anti-DYNC1I2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:5000
IF: 1:10-1:100
Immunogen
Fusion protein of DYNC1I2
Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32199 / sc-32200 / sc-66866
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
70,485 Da
NCBI Official Full Name
DYNC1I2 protein
NCBI Official Synonym Full Names
dynein, cytoplasmic 1, intermediate chain 2
NCBI Official Symbol
DYNC1I2
NCBI Official Synonym Symbols
IC2; DNCI2
NCBI Protein Information
cytoplasmic dynein 1 intermediate chain 2; DH IC-2; dynein intermediate chain 2, cytosolic; dynein, cytoplasmic, intermediate polypeptide 2
UniProt Protein Name
Cytoplasmic dynein 1 intermediate chain 2
Protein Family
UniProt Gene Name
DYNC1I2
UniProt Synonym Gene Names
DNCI2; DNCIC2; DH IC-2
UniProt Entry Name
DC1I2_HUMAN

NCBI Description

This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Uniprot Description

DYNC1I2: intermediate chain 2 of dynein. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. The dynein complex is involved in microtubule motor activity and consists of at least two heavy chains and a number of intermediate and light chains.

Protein type: Microtubule-binding; Motor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: centrosome; microtubule; cytoplasmic dynein complex; cytoplasm; cytosol; vesicle

Molecular Function: microtubule motor activity

Biological Process: viral reproduction; transport; metabolic process; organelle organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; mitotic cell cycle; G2/M transition of mitotic cell cycle; microtubule-based movement

Research Articles on DYNC1I2

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Product Notes

The DYNC1I2 dync1i2 (Catalog #AAA2527348) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYNC1I2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DYNC1I2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:5000 IF: 1:10-1:100. Researchers should empirically determine the suitability of the DYNC1I2 dync1i2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYNC1I2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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