Chromosome alignment-maintaining phosphoprotein 1 (CHAMP1) Recombinant Protein | CHAMP1 recombinant protein

Recombinant Human Chromosome alignment-maintaining phosphoprotein 1 (CHAMP1) , partial

• Gene Names: CHAMP1; CAMP; CHAMP; MRD40; ZNF828; C13orf8
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Chromosome alignment-maintaining phosphoprotein 1 (CHAMP1); Recombinant Human Chromosome alignment-maintaining phosphoprotein 1 (CHAMP1); partial; CHAMP1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 812

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 255918139
• NCBI GeneID: 283489
• NCBI Accession #: NP_001157616.1
• NCBI GenBank Nucleotide #: NM_001164144.2
• UniProt Accession #: Q96JM3; Q6P181; Q8NC88; Q9BST0; B3KU06
• Molecular Weight: 89,099 Da
• NCBI Official Full Name: chromosome alignment-maintaining phosphoprotein 1
• NCBI Official Synonym Full Names: chromosome alignment maintaining phosphoprotein 1
• NCBI Official Symbol: CHAMP1
• NCBI Official Synonym Symbols: CAMP; CHAMP; MRD40; ZNF828; C13orf8
• NCBI Protein Information: chromosome alignment-maintaining phosphoprotein 1
• UniProt Protein Name: Chromosome alignment-maintaining phosphoprotein 1
• Protein Family: Chromosome alignment-maintaining phosphoprotein
• UniProt Gene Name: CHAMP1
• UniProt Synonym Gene Names: C13orf8; CAMP; CHAMP; KIAA1802; ZNF828

NCBI Description

This gene encodes a zinc finger protein that functions as a regulator of chromosome segregation in mitosis. The encoded protein is required for correct alignment of chromosomes on the metaphase plate, and plays a role in maintaining the attachment of sister kinetochores to microtubules from opposite spindle poles. Mutations in this gene are associated with an autosomal dominant form of intellectual disability. [provided by RefSeq, Jul 2017]

Uniprot Description

Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.