Zinc finger MIZ domain-containing protein 1 (ZMIZ1) Recombinant Protein | ZMIZ1 recombinant protein

Recombinant Human Zinc finger MIZ domain-containing protein 1 (ZMIZ1) , partial

• Gene Names: ZMIZ1; MIZ; RAI17; ZIMP10; TRAFIP10
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zinc finger MIZ domain-containing protein 1 (ZMIZ1); Recombinant Human Zinc finger MIZ domain-containing protein 1 (ZMIZ1); partial; ZMIZ1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 997

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 31543543
• NCBI GeneID: 57178
• NCBI Accession #: NP_065071.1
• NCBI GenBank Nucleotide #: NM_020338.3
• UniProt Accession #: Q9ULJ6; Q5JSH9; Q7Z7E6
• Molecular Weight: 107,270 Da
• NCBI Official Full Name: zinc finger MIZ domain-containing protein 1
• NCBI Official Synonym Full Names: zinc finger MIZ-type containing 1
• NCBI Official Symbol: ZMIZ1
• NCBI Official Synonym Symbols: MIZ; RAI17; ZIMP10; TRAFIP10
• NCBI Protein Information: zinc finger MIZ domain-containing protein 1
• UniProt Protein Name: Zinc finger MIZ domain-containing protein 1
• Protein Family: Zinc finger MIZ domain-containing protein
• UniProt Gene Name: ZMIZ1
• UniProt Synonym Gene Names: KIAA1224; RAI17; ZIMP10

NCBI Description

This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]

Uniprot Description

Acts as transcriptional coactivator. Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation (PubMed:14609956, PubMed:26522984). Involved in transcriptional activation of a subset of NOTCH1 target genes including MYC. Involved in thymocyte and T cell development ().