Succinate-semialdehyde dehydrogenase, mitochondrial (Aldh5a1) Recombinant Protein | Aldh5a1 recombinant protein
Recombinant Mouse Succinate-semialdehyde dehydrogenase, mitochondrial (Aldh5a1)
Gene Names
Aldh5a1; Ahd1; Ahd-1; SSADH; Ssdh1; 6330403E24Rik; D630032B01Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Succinate-semialdehyde dehydrogenase; mitochondrial (Aldh5a1); Recombinant Mouse Succinate-semialdehyde dehydrogenase; Aldh5a1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
36-523, full length protein
Sequence
ASGPGGLHADLLRGDSFVGGRWLPAPATFPVYDPASGAKLGTVADCGVPEARAAVRAAYDAFNSWKGVSVKERSLLLRKWYDLMIQNKDDLAKIITAESGKPLKEAQGEILYSALFLEWFSEEARRIYGDIIYTSAKDKRGLVLKQPVGVAAIITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPYSALALAQLANQAGIPAGVYNVIPCSRNKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVAKGATVVTGGKRHQSGGNFFEPTLLSNVTRDMLCITEETFGPLAPVIKFDKEEEAVAIANAAEVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLEVKYVCYGGL
Sequence Length
488
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Aldh5a1 recombinant protein
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,968 Da
NCBI Official Full Name
succinate-semialdehyde dehydrogenase, mitochondrial
NCBI Official Synonym Full Names
aldhehyde dehydrogenase family 5, subfamily A1
NCBI Official Symbol
Aldh5a1
NCBI Official Synonym Symbols
Ahd1; Ahd-1; SSADH; Ssdh1; 6330403E24Rik; D630032B01Rik
NCBI Protein Information
succinate-semialdehyde dehydrogenase, mitochondrial
UniProt Protein Name
Succinate-semialdehyde dehydrogenase, mitochondrial
UniProt Gene Name
Aldh5a1
Uniprot Description
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Research Articles on Aldh5a1
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Product Notes
The Aldh5a1 aldh5a1 (Catalog #AAA1299809) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 36-523, full length protein. The amino acid sequence is listed below: ASGPGGLHAD LLRGDSFVGG RWLPAPATFP VYDPASGAKL GTVADCGVPE ARAAVRAAYD AFNSWKGVSV KERSLLLRKW YDLMIQNKDD LAKIITAESG KPLKEAQGEI LYSALFLEWF SEEARRIYGD IIYTSAKDKR GLVLKQPVGV AAIITPWNFP SAMITRKVGA ALAAGCTVVV KPAEDTPYSA LALAQLANQA GIPAGVYNVI PCSRNKAKEV GEVLCTDPLV SKISFTGSTA TGKILLHHAA NSVKRVSMEL GGLAPFIVFD SANVDQAVAG AMASKFRNAG QTCVCSNRFL VQRGIHDSFV TKFAEAMKKS LRVGNGFEEG TTQGPLINEK AVEKVEKQVN DAVAKGATVV TGGKRHQSGG NFFEPTLLSN VTRDMLCITE ETFGPLAPVI KFDKEEEAVA IANAAEVGLA GYFYSQDPAQ IWRVAEQLEV GMVGVNEGLI SSVECPFGGV KQSGLGREGS KYGIDEYLEV KYVCYGGL. It is sometimes possible for the material contained within the vial of "Succinate-semialdehyde dehydrogenase, mitochondrial (Aldh5a1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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