WDR62 cdna clone
WDR62 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
Uniprot Description
WDR62: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 19q13.12
Cellular Component: centrosome; nucleus; spindle pole
Molecular Function: protein binding
Biological Process: centriole replication; cerebral cortex development; mitotic spindle organization and biogenesis; neurogenesis
Disease: Microcephaly 2, Primary, Autosomal Recessive, With Or Without Cortical Malformations
Research Articles on WDR62
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Product Notes
The WDR62 wdr62 (Catalog #AAA1278452) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaagcccg agagtctgga gaactccatt ctggattcac tggagccaca gagcctggcc agcctgctga gtgagtcaga gagtccccag gaagctggcc gcgggcaccc ctccttcctg ccccagcaga aggaatcatc tgaggccagt gagctcatcc tctactctct ggaggcagaa gtgacagtca cagggacaga cagccagtat tgcaggaagg aggtggaggc cgggcctgga gaccagcagg gcgactccta cctcagggtg tcctccgaca gcccaaagga ccagagcccg cctgaggact cgggggagtc agaggccgac ctggagtgca gcttcgcagc catccactcc ccagctccgc ctcctgaccc tgcccctcgg tttgccacgt cgctgcccca tttcccagga tgcgcaggtc ccacagaaga tgagctgtcc ctgcccgagg gacccagcgt ccccagcagc tccctacccc agactccgga gcaggagaag ttcctccgcc accactttga gacactgact gagtccccct gcagagctct gggagacgtg gaggcctctg aagctgaaga ccacttcttc aacccacgcc tgagtatctc cacgcagttc ctctcaagcc tccagaaggc atccaggttc acccatacct tccctccccg ggcaacccag tgccttgtga agtctccaga ggtcaagctc atggaccgag gcggaagcca gcccagagca ggtactggct acgcctcccc agacaggacc cacgtccttg ctgcagggaa ggctgaagag accctggagg cctggcgccc accacctccc tgccttacga gcctggcgtc ctgtgtccct gcttcctccg tgctgcccac agacaggaat ctcccaacgc ccacatctgc acccacccca ggcctggctc agggtgtcca tgccccctcc acctgttcct acatggaggc cactgccagc tcccgtgcca ggatatcacg cagcatctcc ctcggtgaca gtgagggccc tatcgtggcc acactggccc agcccctccg taggccatcg tccgttgggg agctggcctc cttgggccag gagcttcagg ccatcaccac cgcgacaaca cccagtttgg acagtgaggg ccaagagcct gccctgcgtt cctggggcaa ccacgaggcc cgggccaacc tgagactgac cctgtcaagt gcctgtgatg ggctcctgct gccccccgtg gatacccagc ctggcgtcac cgtccctgca gtgagcttcc cagcccctag ccctgtggaa gagagcgccc tgaggctcca cggctctgcc tttcgcccaa gtctcccagc tcctgagtcc cctggccttc ctgcccaccc cagtaacccc cagcttccag aggcccggcc tggcatccct ggcagcactg cctccctcct ggagcccacc tccggtgcac ttggtctgtt ccagggcagc cctgcccgct ggagtgagcc ctgggtgccg gttgaagccc tgcccccatc tccccttgag ctgagcaggg tggggaacat cttgcacagg ctgcagacca ccttccaaga agccctcgac ctttaccgtg tgttggtctc cagtggccag gtggacaccg ggcagcagca ggcacggact gagctggtct ccaccttcct gtggatccac agccagctgg aggctgaatg cctggtgggg actagtgtgg ccccagccca ggctctgccc agcccaggac ccccgtcccc accgacgctg taccccctgg ccagcccaga cctgcaggcc ctgctggaac actactcgga gctgctggtg caggccgtgc ggaggaaggc acgggggcac tga. It is sometimes possible for the material contained within the vial of "WDR62, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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