CLIP1 cdna clone
CLIP1 cDNA Clone
Gene Names
CLIP1; RSN; CLIP; CYLN1; CLIP170; CLIP-170
Synonyms
CLIP1; CLIP1 cDNA Clone; CLIP1 cdna clone
Sequence
atgagtatgctaaagccaagtgggcttaaggcccccaccaagatcctgaagcctggaagcacagctctgaagacacctacggctgttgtagctccagtagaaaaaaccatatccagtgaaaaagcatcaagcactccatcatctgagactcaggaggaatttgtggatgactttcgagttggggagcgagtttgggtgaatggaaataagcctggatttatccagtttcttggagaaacccagtttgcaccaggccagtgggctggaattgttttagatgaacccataggcaagaacgatggttcggtggcaggagttcggtatttccagtgtgaacctttaaagggcatatttacccgaccttcaaagttaacaaggaaggtgcaagcagaagatgaagctaatggcctgcagacaacgcccgcctcccgagctacttcaccgctgtgcacttctacggccagcatggtgtcttcctccccctccaccccttcaaacatccctcagaaaccatcacagccagcagcaaaggaaccttcagctacgcctccgatcagcaaccttacaaaaactgccagtgaatctatctccaacctttcagaggctggctcaatcaagaaaggagaaagagagctcaaaatcggagacagagtattggttggtggcactaaggctggtgtagtccggtttcttggggagaccgactttgccaagggggagtggtgtggcgtggagttagatgagccacttgggaagaatgatggcgctgttgctggaacaaggtattttcagtgtcaacccaaatatggcttgttcgctcctgtccacaaagttaccaagattggcttcccttccactacaccagccaaagccaaggccaacgcagtgaggcgagtgatggcgaccacgtccgccagcctgaagcgcagcccttctgcctcttccctcagctccatgagctcagtggcctcctctgtgagcagcaggcccagtcggacaggactattgactgaaacctcctcccgttacgccaggaagatctccggtaccactgccctccaggaggccctgaaggagaagcagcagcacattgagcagctgctggcggaacgggatctggagagggcggaggtggccaaggccacgagccacgtgggggagatagagcaggagctagctctggcccgggacggacatgaccagcatgtcctggaattggaagccaaaatggaccagctgcgaacaatggtggaagctgctgacagggagaaggtggagcttctcaaccagcttgaagaggagaaaaggaaggttgaggaccttcagttccgggttgaagaagaatcaattaccaaaggtgatcttgagcaaaagagccagatttctgaagatcctgagaatacgcagaccaaactggagcatgcccgcattaaggagcttgaacagagcctgctctttgaaaagaccaaagctgacaaactccagagggagttagaagacactagggtggctacagtttcagaaaagtcacgtataatggaactggagaaagacctagcattgagagtacaggaagtagctgagctccgaagaaggctagagtccaataagcctgctggggatgtggacatgtcactttcccttttgcaagagataagctctttgcaagaaaagttagaagtcacccgtactgaccaccagagagaaataacttctctgaaggagcattttggagcccgggaagaaactcatcagaaggagataaaggctctgtataccgccacggaaaagctttccaaagagaacgagtcattgaaaagcaagctggagcatgccaacaaagagaactcagatgtgatagctctatggaagtccaaactggagactgccatcgcatcccaccagcaggcgatggaagaactgaaggtatctttcagcaaagggcttggaacagagacggcagaatttgctgaactaaaaacacaaatagagaaaatgagactagattaccaacacgaaatagaaaatttgcagaatcaacaagactctgaacgggctgcccatgctaaagagatggaagccttgagggctaaactgatgaaagttattaaagaaaaggaaaacagtctggaagccatcaggtcgaaactggacaaagcagaagaccagcatctcgtagaaatggaagacacgttaaacaaattacaggaagctgaaataaaggtaaaggagctagaggtactgcaagccaaatgcaatgaacaaaccaaggttattgataattttacatcacagctcaaggctactgaagaaaagctcttggatcttgatgcacttcggaaagccagttccgaaggtaaatcggaaatgaagaaacttagacagcagcttgaggcagctgagaaacagattaaacatttagagattgaaaagaatgctgaaagtagcaaggctagtagcattaccagagagctccaggggagagagctaaagcttactaaccttcaggaaaatttgagtgaagtcagtcaagtgaaagagactttggaaaaagaacttcagattttgaaagaaaagtttgctgaagcttcagaggaggcagtctctgttcagagaagtatgcaagaaactgtaaataagttacaccaaaaggaggaacagtttaacatgctgtcttctgacttggagaagctgagagaaaacttagcagatatggaggcaaaatttagagagaaagatgagagagaagagcagctgataaaggcaaaggaaaaactggaaaatgacattgcagaaataatgaagatgtcaggagataacccttctcagctgacaaaaatgaacgatgaattacgtctgaaagaaagagatgtagaagaattacagctaaaacttacaaaggctaatgaaaatgcaagttttctgcaaaaaagtattgaggacatgactgtcaaagctgaacagagccagcaagaagcagctaaaaagcatgaggaagaaaagaaagaattggagaggaaattgtcggacctggaaaagaaaatggaaacaagccacaaccagtgtcaggagctgaaagccaggtatgagagagccacttctgagacaaaaaccaagcatgaagaaatcctacagaacctccagaagacgctgctggacacagaggacaagctgaagggcgcacgggaggagaacagtggcttgctgcaggagctggaggagctgagaaagcaagccgagaaagccaaagctgctcaaacagcggaagatgccatgcagataatggaacagatgaccaaagagaagactgagactctggcctccttggaggacaccaagcaaacaaatgcaaaactacagaatgaattggacacacttaaagaaaacaacttgaaaaatgtggaagagctgaacaaatcaaaagaactcctgactgtagagaatcaaaaaatggaagaatttaggaaagaaatagaaaccctaaagcaggcagcagctcagaagtcccagcagctttcagcgttgcaagaagagaacgttaaacttgctgaggagctggggagaagcagggacgaagtcacaagtcatcaaaagctggaagaagaaagatctgtgctcaataatcagttgttagaaatgaaaaaaagagaatccaagttcataaaagacgcagatgaagagaaagcttccttgcagaaatccatcagtataactagtgccttactcacagaaaaggatgccgagctggagaaactgagaaatgaggtcacagtgctcaggggagaaaacgcctctgccaagtccttgcattcagttgttcagactctagagtctgataaggtgaagctcgagctcaaggtaaagaacttggagcttcaactcaaagaaaacaagaggcagctcagcagctcctcaggtaatacagacactcaggcagacgaggatgaaagagcccaggagagtcagattgatttcctaaattcagtaatagtggaccttcaaaggaagaatcaagacctcaagatgaaggtggagatgatgtcagaagcagccctgaatgggaacggggatgacctaaacaattatgacagtgatgatcaggagaaacagtccaagaagaaacctcgcctcttctgtgacatttgtgactgctttgatctccacgacacagaggattgtcctacccaggcacagatgtcagaggaccctccccattccacacaccatggcagtcggggtgaggaacgcccatactgtgaaatctgtgagatgtttggacactgggccaccaactgcaatgacgacgaaaccttctga
Sequence Length
4317
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
156,781 Da
NCBI Official Full Name
Homo sapiens CAP-GLY domain containing linker protein 1, mRNA
NCBI Official Synonym Full Names
CAP-Gly domain containing linker protein 1
NCBI Official Symbol
CLIP1
NCBI Official Synonym Symbols
RSN; CLIP; CYLN1; CLIP170; CLIP-170
NCBI Protein Information
CAP-Gly domain-containing linker protein 1
UniProt Protein Name
CAP-Gly domain-containing linker protein 1
Protein Family
UniProt Gene Name
CLIP1
UniProt Synonym Gene Names
CYLN1; RSN; CLIP-170
UniProt Entry Name
CLIP1_HUMAN
NCBI Description
The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
Restin: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. Interacts with MTOR; phosphorylates and regulates CLIP1. Interacts (via CAP-Gly domains) with tubulin. Interacts with SLAIN2. Interacts (via zinc finger) with DCTN1. Interacts with MAPRE1 and MAPRE3. Detected in dendritic cells. Highly expressed in the Reed-Sternberg cells of Hodgkin disease. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 12q24.3
Cellular Component: centrosome; cytoplasm; cytosol; endosome; intermediate filament; kinetochore; microtubule; microtubule cytoskeleton
Molecular Function: microtubule binding; microtubule plus-end binding; protein binding; protein homodimerization activity; tubulin binding; zinc ion binding
Biological Process: microtubule bundle formation; mitosis; positive regulation of microtubule polymerization; sister chromatid cohesion
Research Articles on CLIP1
Similar Products
Product Notes
The CLIP1 clip1 (Catalog #AAA1278249) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagtatgc taaagccaag tgggcttaag gcccccacca agatcctgaa gcctggaagc acagctctga agacacctac ggctgttgta gctccagtag aaaaaaccat atccagtgaa aaagcatcaa gcactccatc atctgagact caggaggaat ttgtggatga ctttcgagtt ggggagcgag tttgggtgaa tggaaataag cctggattta tccagtttct tggagaaacc cagtttgcac caggccagtg ggctggaatt gttttagatg aacccatagg caagaacgat ggttcggtgg caggagttcg gtatttccag tgtgaacctt taaagggcat atttacccga ccttcaaagt taacaaggaa ggtgcaagca gaagatgaag ctaatggcct gcagacaacg cccgcctccc gagctacttc accgctgtgc acttctacgg ccagcatggt gtcttcctcc ccctccaccc cttcaaacat ccctcagaaa ccatcacagc cagcagcaaa ggaaccttca gctacgcctc cgatcagcaa ccttacaaaa actgccagtg aatctatctc caacctttca gaggctggct caatcaagaa aggagaaaga gagctcaaaa tcggagacag agtattggtt ggtggcacta aggctggtgt agtccggttt cttggggaga ccgactttgc caagggggag tggtgtggcg tggagttaga tgagccactt gggaagaatg atggcgctgt tgctggaaca aggtattttc agtgtcaacc caaatatggc ttgttcgctc ctgtccacaa agttaccaag attggcttcc cttccactac accagccaaa gccaaggcca acgcagtgag gcgagtgatg gcgaccacgt ccgccagcct gaagcgcagc ccttctgcct cttccctcag ctccatgagc tcagtggcct cctctgtgag cagcaggccc agtcggacag gactattgac tgaaacctcc tcccgttacg ccaggaagat ctccggtacc actgccctcc aggaggccct gaaggagaag cagcagcaca ttgagcagct gctggcggaa cgggatctgg agagggcgga ggtggccaag gccacgagcc acgtggggga gatagagcag gagctagctc tggcccggga cggacatgac cagcatgtcc tggaattgga agccaaaatg gaccagctgc gaacaatggt ggaagctgct gacagggaga aggtggagct tctcaaccag cttgaagagg agaaaaggaa ggttgaggac cttcagttcc gggttgaaga agaatcaatt accaaaggtg atcttgagca aaagagccag atttctgaag atcctgagaa tacgcagacc aaactggagc atgcccgcat taaggagctt gaacagagcc tgctctttga aaagaccaaa gctgacaaac tccagaggga gttagaagac actagggtgg ctacagtttc agaaaagtca cgtataatgg aactggagaa agacctagca ttgagagtac aggaagtagc tgagctccga agaaggctag agtccaataa gcctgctggg gatgtggaca tgtcactttc ccttttgcaa gagataagct ctttgcaaga aaagttagaa gtcacccgta ctgaccacca gagagaaata acttctctga aggagcattt tggagcccgg gaagaaactc atcagaagga gataaaggct ctgtataccg ccacggaaaa gctttccaaa gagaacgagt cattgaaaag caagctggag catgccaaca aagagaactc agatgtgata gctctatgga agtccaaact ggagactgcc atcgcatccc accagcaggc gatggaagaa ctgaaggtat ctttcagcaa agggcttgga acagagacgg cagaatttgc tgaactaaaa acacaaatag agaaaatgag actagattac caacacgaaa tagaaaattt gcagaatcaa caagactctg aacgggctgc ccatgctaaa gagatggaag ccttgagggc taaactgatg aaagttatta aagaaaagga aaacagtctg gaagccatca ggtcgaaact ggacaaagca gaagaccagc atctcgtaga aatggaagac acgttaaaca aattacagga agctgaaata aaggtaaagg agctagaggt actgcaagcc aaatgcaatg aacaaaccaa ggttattgat aattttacat cacagctcaa ggctactgaa gaaaagctct tggatcttga tgcacttcgg aaagccagtt ccgaaggtaa atcggaaatg aagaaactta gacagcagct tgaggcagct gagaaacaga ttaaacattt agagattgaa aagaatgctg aaagtagcaa ggctagtagc attaccagag agctccaggg gagagagcta aagcttacta accttcagga aaatttgagt gaagtcagtc aagtgaaaga gactttggaa aaagaacttc agattttgaa agaaaagttt gctgaagctt cagaggaggc agtctctgtt cagagaagta tgcaagaaac tgtaaataag ttacaccaaa aggaggaaca gtttaacatg ctgtcttctg acttggagaa gctgagagaa aacttagcag atatggaggc aaaatttaga gagaaagatg agagagaaga gcagctgata aaggcaaagg aaaaactgga aaatgacatt gcagaaataa tgaagatgtc aggagataac ccttctcagc tgacaaaaat gaacgatgaa ttacgtctga aagaaagaga tgtagaagaa ttacagctaa aacttacaaa ggctaatgaa aatgcaagtt ttctgcaaaa aagtattgag gacatgactg tcaaagctga acagagccag caagaagcag ctaaaaagca tgaggaagaa aagaaagaat tggagaggaa attgtcggac ctggaaaaga aaatggaaac aagccacaac cagtgtcagg agctgaaagc caggtatgag agagccactt ctgagacaaa aaccaagcat gaagaaatcc tacagaacct ccagaagacg ctgctggaca cagaggacaa gctgaagggc gcacgggagg agaacagtgg cttgctgcag gagctggagg agctgagaaa gcaagccgag aaagccaaag ctgctcaaac agcggaagat gccatgcaga taatggaaca gatgaccaaa gagaagactg agactctggc ctccttggag gacaccaagc aaacaaatgc aaaactacag aatgaattgg acacacttaa agaaaacaac ttgaaaaatg tggaagagct gaacaaatca aaagaactcc tgactgtaga gaatcaaaaa atggaagaat ttaggaaaga aatagaaacc ctaaagcagg cagcagctca gaagtcccag cagctttcag cgttgcaaga agagaacgtt aaacttgctg aggagctggg gagaagcagg gacgaagtca caagtcatca aaagctggaa gaagaaagat ctgtgctcaa taatcagttg ttagaaatga aaaaaagaga atccaagttc ataaaagacg cagatgaaga gaaagcttcc ttgcagaaat ccatcagtat aactagtgcc ttactcacag aaaaggatgc cgagctggag aaactgagaa atgaggtcac agtgctcagg ggagaaaacg cctctgccaa gtccttgcat tcagttgttc agactctaga gtctgataag gtgaagctcg agctcaaggt aaagaacttg gagcttcaac tcaaagaaaa caagaggcag ctcagcagct cctcaggtaa tacagacact caggcagacg aggatgaaag agcccaggag agtcagattg atttcctaaa ttcagtaata gtggaccttc aaaggaagaa tcaagacctc aagatgaagg tggagatgat gtcagaagca gccctgaatg ggaacgggga tgacctaaac aattatgaca gtgatgatca ggagaaacag tccaagaaga aacctcgcct cttctgtgac atttgtgact gctttgatct ccacgacaca gaggattgtc ctacccaggc acagatgtca gaggaccctc cccattccac acaccatggc agtcggggtg aggaacgccc atactgtgaa atctgtgaga tgtttggaca ctgggccacc aactgcaatg acgacgaaac cttctga. It is sometimes possible for the material contained within the vial of "CLIP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
