SYNJ2 cdna clone
SYNJ2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Uniprot Description
SYNJ2: Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis. Belongs to the synaptojanin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.36; Motility/polarity/chemotaxis; Phosphatase (non-protein); Carbohydrate Metabolism - inositol phosphate
Chromosomal Location of Human Ortholog: 6q25.3
Cellular Component: cytosol
Molecular Function: phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; phosphatidylinositol-3-phosphatase activity; phosphoinositide 5-phosphatase activity; protein binding
Biological Process: phosphatidylinositol biosynthetic process
Research Articles on SYNJ2
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Product Notes
The SYNJ2 synj2 (Catalog #AAA1277820) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggggggca aggcggggaa caagggcgcc gtcggcatcc gcttccagtt ccacagcacc agcttctgct tcatatgtag tcacctgacg gccgggcagt cccaggtgaa ggagcggaat gaagactaca aggagatcac ccagaaactc tgcttcccaa tggggagaaa tgttttttct catgattatg tattttggtg tggcgatttc aactaccgca ttgatcttac ttatgaagaa gtcttctatt ttgttaaacg ccaagactgg aagaaacttc tggaatttga tcaactacag ctacagaaat caagtggaaa aatttttaag gactttcacg aaggagccat taactttgga cccacctaca agtatgacgt cggctcagcc gcctacgata caagcgacaa atgccgcacc cccgcctgga cagacagggt gctgtggtgg aggaagaaac atccctttga taaaacagct ggagaactca accttctaga cagtgatcta gatgttgaca ccaaagtcag acacacctgg tctcctggtg ccctgcagta ttatggtcgt gcggagctac aagcttctga tcacagacct gtgctggcga tcgtggaggt ggaagttcag gaagtcgatg tgggtgctcg ggagagggtt ttccaggaag tgtcctcctt ccagggcccc ctggatgcca ctgttgtagt aaaccttcaa tcaccgacct tagaagagaa aaacgagttt ccagaggacc tgcgtactga gctcatgcag accttgggga gttatgggac aattgttctt gtcaggatca accaagggca gatgctggta acttttgcag acagtcactc ggctctcagt gtcctggacg tggacggtat gaaggtgaaa ggcagagcag tgaagattag accgaagacc aaggactggc tgaaaggttt gcgagaggag atcattcgga aacgagacag catggccccc gtgtctccca ctgccaactc ctgtttgctg gaggaaaact ttgacttcac aagtttggac tatgagtcag aaggggatat tcttgaagac gatgaagact acttggtgga tgaattcaat cagcctgggg tctcggacag tgaactcggg ggagacgacc tctctgatgt ccccggcccc acagcactgg ctcctcccag caagtcacct gctctcacca aaaagaagca gcatccaacg tacaaagatg acgcggacct ggtggagctc aagcgggagc tggaagccgt cggggagttc cgccaccgtt ctccgagcag gtctctgtcg gtccccaacc gacctcggcc acctcaaccc ccgcagagac ccccccctcc aaccggttta atggtgaaaa agtcggcttc agatgcgtcc atctcctccg gcacccatgg gcagtattca attttgcaga cggcaagact tctaccagga gcacctcagc aacctcccaa ggctcggact ggaataagta aaccttataa tgtcaagcag atcaaaacca ccaatgccca ggaggcagaa gcagcaatcc ggtgtctcct ggaagccaga ggaggtgcct ccgaagaagc cctaagtgcc gtggccccaa gggaccttga agcatcctct gaaccagagc ccacaccggg ggcagccaaa ccagagaccc cacaggcgcc cccactcctt ccccgtcggc ccccacccag agttcctgcc atcaagaagc caaccttgag aaggacagga aagcccctgt caccggaaga acagtttgag caacagactg tccattttac aatcgggccc ccggagacaa gcgttgaggc ccctcctgtc gtgacagccc ctcgagtccc tcctgttccc aaaccaagaa catttcagcc tgggaaagct gcagagaggc caagccacag gaagccagca tcagacgaag cccctcctgg ggcaggagcc tctgtgccac cacctctgga ggcgccgcct cttgtgccca aggtaccccc gaggaggaag aagtcagccc ccgcagcctt ccacctgcag gtcctgcaga gcaacagcca gcttctccag ggcctcactt acaatagcag tgacagcccc tctgggcacc cacctgccgc gggcaccgtc ttcccacaag gggactttct cagcacttca tctgctacaa gccccgacag cgatggcacc aaagcgatga agccagaggc agccccactt cttggtgatt atcaggaccc cttctggaac cttcttcacc accctaaact gttgaataac acttggcttt ctaagagctc agaccctttg gactcaggaa ccaggagccc caaaagagat cccatagacc cagtgtcagc tggcgcttca gctgccaagg cagagctgcc accagatcat ggacacaaaa ccttaggtca ctgggtgaca atcagtgacc aagaaaagag gacagcactg caggtgtttg acccactggc aaaaacatga. It is sometimes possible for the material contained within the vial of "SYNJ2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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