L3MBTL3 cdna clone
L3MBTL3 cDNA Clone
Gene Names
L3MBTL3; MBT1; MBT-1
Synonyms
L3MBTL3; L3MBTL3 cDNA Clone; L3MBTL3 cdna clone
Sequence
atgactgaatctgcctctagcacaagtggtcaagagtttgatgtgttcagtgttatggactggaaagatggagtgggcacgttaccaggaagtgacttaaagtttcgggtaaatgagtttggagccctggaagttattacagatgagaatgagatggaaaatgttaaaaaagcaactgctaccaccacttggatggtaccaactgctcaagaagtcttttcagagaagactgggatgcctttcaggttgaaggatccagtgaaagtagaagggcttcagttctgtgagaactgttgtcagtatggcaacgtagatgagtgtctttctggaggaaactattgcagccagaattgtgctcggcacatcaaagataaagatcagaaggaagaaagggacgtagaagaagacaatgaggaagaagatcctaagtgtagtcggaagaaaaaaccaaaattatctctgaaagctgacaacaaggaggatggagaagagagagatgatgaaatggagaacaaacaagatgtaagaatcctgaggggttcgcagagagcacggaggaaaagacgaggggattcggctgtactaaagcagggtttgcctcctaaaggaaagaaagcgtggtgctgggcatcctacctggaagaggagaaagcggtggcagtgccggcgaagctgttcaaggagcatcaatcctttccatataacaaaaatggattcaaagttggcatgaaattagaaggcgtggatcccgagcatcagtctgtgtactgtgtcctcaccgtcgcggaggtttgtggataccggataaagcttcactttgatgggtattctgattgctatgacttctgggtgaatgcagacgctctggatatccacccagttgggtggtgtgagaaaaccggccacaaactccatcctccaaaagggtataaagaagaagaattcaattggcagacctatcttaagacatgtaaagctcaagctgctcctaagtcattatttgaaaatcagaatataacagtgatcccatcgggctttcgagttggtatgaagcttgaggcagtagacaaaaagaatccctcattcatctgtgttgctacggtaacagatatggtggacaatcgtttcctggtacattttgacaactgggatgagagctatgactattggtgtgaagcatcaagtccacatattcatccagttggttggtgtaaggaacatagaagaacccttattactccaccaggttatccaaatgtgaaacatttttcttgggataaatacttagaagaaaccaattctttacctgctcctgcaagagctttcaaagtgaaacctcctcatggattccagaaaaaaatgaagcttgaggttgtagacaaaaggaaccctatgtttattagagtagcaactgtggcagacacagatgatcaccgggtaaaagttcactttgatggctggaacaattgctatgattactggatagatgcagattctcctgatattcaccctgtaggctggtgttcaaaaacaggacatccccttcagcctcctttgagccccttagaattaatggaagcttcagaacatggtggatgctcaaccccgggatgtaaagggattggccatttcaagagagcgagacatctgggccctcacagtgctgccaactgtccctattcagaaatcaatttgaataaagaccgtatttttccagaccgcttaagtggtgagatgcctccggctagtccgtcatttccaagaaataaaaggacagatgcaaatgaaagctcttcttcccctgaaatcagagaccagcatgctgatgatgtcaaagaagactttgaagagagaacagaaagtgaaatgagaacatcacatgaagccagaggtgcccgggaagaacccaccgtccagcaggcacagcgtcggtcagctgtctttctgtcctttaagtccccaattccatgtctgcccttgcgctgggagcagcaaagcaaacttcttccaactgtcgcaggaatccctgccagtaaagtttccaaatggagcacagacgaggtgtcagaatttatacagagcttacctgggtgtgaagaacatggaaaggtatttaaagatgaacaaattgatggagaagcatttctacttatgactcaaacagacattgttaaaattatgagcattaaactgggccctgctctcaaaattttcaattccatcctgatgttcaaagctgcagagaagaattctcacaatgaactttga
Sequence Length
2268
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
85,757 Da
NCBI Official Full Name
Homo sapiens l(3)mbt-like 3 (Drosophila), mRNA
NCBI Official Synonym Full Names
l(3)mbt-like 3 (Drosophila)
NCBI Official Symbol
L3MBTL3
NCBI Official Synonym Symbols
MBT1; MBT-1
NCBI Protein Information
lethal(3)malignant brain tumor-like protein 3
UniProt Protein Name
Lethal(3)malignant brain tumor-like protein 3
Protein Family
UniProt Gene Name
L3MBTL3
UniProt Synonym Gene Names
KIAA1798; MBT1; H-l(3)mbt-like protein 3; L(3)mbt-like protein 3
UniProt Entry Name
LMBL3_HUMAN
Uniprot Description
L3MBTL3: a Polycomb group (PcG) protein that regulates the maturation of myeloid progenitor cells. May influence myelopoiesis by transiently enhancing p57(KIP2) expression levels. PcG proteins participate in DNA-binding complexes with gene-repressing activity, many of which have been highlighted for their involvement in hematopoiesis. A member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. Contains a SAM domain, a common protein modules found in eukaryotic proteomes. Many SAM domains have been shown to form helical polymer structures. May create large protein complexes in the cell. Two isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 6q23
Molecular Function: protein binding
Research Articles on L3MBTL3
Similar Products
Product Notes
The L3MBTL3 l3mbtl3 (Catalog #AAA1276745) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgactgaat ctgcctctag cacaagtggt caagagtttg atgtgttcag tgttatggac tggaaagatg gagtgggcac gttaccagga agtgacttaa agtttcgggt aaatgagttt ggagccctgg aagttattac agatgagaat gagatggaaa atgttaaaaa agcaactgct accaccactt ggatggtacc aactgctcaa gaagtctttt cagagaagac tgggatgcct ttcaggttga aggatccagt gaaagtagaa gggcttcagt tctgtgagaa ctgttgtcag tatggcaacg tagatgagtg tctttctgga ggaaactatt gcagccagaa ttgtgctcgg cacatcaaag ataaagatca gaaggaagaa agggacgtag aagaagacaa tgaggaagaa gatcctaagt gtagtcggaa gaaaaaacca aaattatctc tgaaagctga caacaaggag gatggagaag agagagatga tgaaatggag aacaaacaag atgtaagaat cctgaggggt tcgcagagag cacggaggaa aagacgaggg gattcggctg tactaaagca gggtttgcct cctaaaggaa agaaagcgtg gtgctgggca tcctacctgg aagaggagaa agcggtggca gtgccggcga agctgttcaa ggagcatcaa tcctttccat ataacaaaaa tggattcaaa gttggcatga aattagaagg cgtggatccc gagcatcagt ctgtgtactg tgtcctcacc gtcgcggagg tttgtggata ccggataaag cttcactttg atgggtattc tgattgctat gacttctggg tgaatgcaga cgctctggat atccacccag ttgggtggtg tgagaaaacc ggccacaaac tccatcctcc aaaagggtat aaagaagaag aattcaattg gcagacctat cttaagacat gtaaagctca agctgctcct aagtcattat ttgaaaatca gaatataaca gtgatcccat cgggctttcg agttggtatg aagcttgagg cagtagacaa aaagaatccc tcattcatct gtgttgctac ggtaacagat atggtggaca atcgtttcct ggtacatttt gacaactggg atgagagcta tgactattgg tgtgaagcat caagtccaca tattcatcca gttggttggt gtaaggaaca tagaagaacc cttattactc caccaggtta tccaaatgtg aaacattttt cttgggataa atacttagaa gaaaccaatt ctttacctgc tcctgcaaga gctttcaaag tgaaacctcc tcatggattc cagaaaaaaa tgaagcttga ggttgtagac aaaaggaacc ctatgtttat tagagtagca actgtggcag acacagatga tcaccgggta aaagttcact ttgatggctg gaacaattgc tatgattact ggatagatgc agattctcct gatattcacc ctgtaggctg gtgttcaaaa acaggacatc cccttcagcc tcctttgagc cccttagaat taatggaagc ttcagaacat ggtggatgct caaccccggg atgtaaaggg attggccatt tcaagagagc gagacatctg ggccctcaca gtgctgccaa ctgtccctat tcagaaatca atttgaataa agaccgtatt tttccagacc gcttaagtgg tgagatgcct ccggctagtc cgtcatttcc aagaaataaa aggacagatg caaatgaaag ctcttcttcc cctgaaatca gagaccagca tgctgatgat gtcaaagaag actttgaaga gagaacagaa agtgaaatga gaacatcaca tgaagccaga ggtgcccggg aagaacccac cgtccagcag gcacagcgtc ggtcagctgt ctttctgtcc tttaagtccc caattccatg tctgcccttg cgctgggagc agcaaagcaa acttcttcca actgtcgcag gaatccctgc cagtaaagtt tccaaatgga gcacagacga ggtgtcagaa tttatacaga gcttacctgg gtgtgaagaa catggaaagg tatttaaaga tgaacaaatt gatggagaag catttctact tatgactcaa acagacattg ttaaaattat gagcattaaa ctgggccctg ctctcaaaat tttcaattcc atcctgatgt tcaaagctgc agagaagaat tctcacaatg aactttga. It is sometimes possible for the material contained within the vial of "L3MBTL3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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