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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using L3MBTL3 antibody.)

Rabbit anti-Human, Mouse L3MBTL3 Polyclonal Antibody | anti-L3MBTL3 antibody

L3MBTL3 Polyclonal Antibody

Gene Names
L3MBTL3; MBT1; MBT-1
Reactivity
Human, Mouse
Applications
Western Blot, Immunofluorescence, Immunoprecipitation
Purity
Affinity purification
Synonyms
L3MBTL3; Polyclonal Antibody; L3MBTL3 Polyclonal Antibody; MBT-1; MBT1; l (3)mbt-like 3 (Drosophila); anti-L3MBTL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 50% glycerol, pH7.4
Applicable Applications for anti-L3MBTL3 antibody
Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:100
IP: 1:50-1:200
Immunogen
Recombinant fusion protein of human L3MBTL3 (NP_001007103.1).
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using L3MBTL3 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using L3MBTL3 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of MCF-7 cells using L3MBTL3 antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of MCF-7 cells using L3MBTL3 antibody.)
Product Categories/Family for anti-L3MBTL3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
88,337 Da
NCBI Official Full Name
lethal(3)malignant brain tumor-like protein 3 isoform b
NCBI Official Synonym Full Names
l(3)mbt-like 3 (Drosophila)
NCBI Official Symbol
L3MBTL3
NCBI Official Synonym Symbols
MBT1; MBT-1
NCBI Protein Information
lethal(3)malignant brain tumor-like protein 3; lethal(3)malignant brain tumor-like protein 3; l(3)mbt-like protein 3; H-l(3)mbt-like protein 3
UniProt Protein Name
Lethal(3)malignant brain tumor-like protein 3
UniProt Gene Name
L3MBTL3
UniProt Synonym Gene Names
KIAA1798; MBT1; H-l(3)mbt-like protein 3; L(3)mbt-like protein 3
UniProt Entry Name
LMBL3_HUMAN

Uniprot Description

L3MBTL3: a Polycomb group (PcG) protein that regulates the maturation of myeloid progenitor cells. May influence myelopoiesis by transiently enhancing p57(KIP2) expression levels. PcG proteins participate in DNA-binding complexes with gene-repressing activity, many of which have been highlighted for their involvement in hematopoiesis. A member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. Contains a SAM domain, a common protein modules found in eukaryotic proteomes. Many SAM domains have been shown to form helical polymer structures. May create large protein complexes in the cell. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 6q23

Cellular Component: nucleus

Biological Process: erythrocyte maturation; macrophage differentiation; regulation of transcription, DNA-dependent; granulocyte differentiation; transcription, DNA-dependent; chromatin modification

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Product Notes

The L3MBTL3 l3mbtl3 (Catalog #AAA9434011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The L3MBTL3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's L3MBTL3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP). WB: 1:500-1:2000 IF: 1:50-1:100 IP: 1:50-1:200. Researchers should empirically determine the suitability of the L3MBTL3 l3mbtl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "L3MBTL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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