GUCY1A3 cdna clone

GUCY1A3 cDNA Clone

Gene Names

GUCY1A3; GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A1

Synonyms

GUCY1A3; GUCY1A3 cDNA Clone; GUCY1A3 cdna clone

Ordering
Cat. Num. AAA1276288 For Research Use Only!

Sequence

atgttctgcacgaagctcaaggatctcaagatcacaggagagtgtcctttctccttactggcaccaggtcaagttcctaacgagtcttcagaggaggcagcaggaagctcagagagctgcaaagcaaccatgcccatctgtcaagacattcctgagaagaacatacaagaaagtcttcctcaaagaaaaaccagtcggagccgagtctatcttcacactttggcagagagtatttgcaaactgattttcccagagtttgaacggctgaatgttgcacttcagagaacattggcaaagcacaaaataaaagaaagcaggaaatctttggaaagagaagactttgaaaaaacaattgcagagcaagcagttgcagcaggagttccagtggaggttatcaaagaatctcttggtgaagaggtttttaaaatatgttacgaggaagatgaaaacatccttggggtggttggaggcacccttaaagattttttaaacagcttcagtacccttctgaaacagagcagccattgccaagaagcaggaaaaaggggcaggcttgaggacgcctccattctatgcctggataaggaggatgattttctacatgtttactacttcttccctaagagaaccacctccctgattcttcccggcatcataaaggcagctgctcacgtattatatgaaacggaagtggaagtgtcgttaatgcctccctgcttccataatgattgcagcgagtttgtgaatcagccctacttgttgtactccgttcacatgaaaagcaccaagccatccctgtcccccagcaaaccccagtcctcgctggtgattcccacatcgctattctgcaagacatttccattccatttcatgtttgacaaagatatgacaattctgcaatttggcaatggcatcagaaggctgatgaacaggagagactttcaaggaaagcctaattttgaagaatactttgaaattctgactccaaaaatcaaccagacgtttagcgggatcatgactatgttgaatatgcagtttgttgtacgagtgaggagatgggacaactctgtgaagaaatcttcaagggttatggacctcaaaggccaaatgatctacattgttgaatccagtgcaatcttgtttttggggtcaccctgtgtggacagattagaagattttacaggacgagggctctacctctcagacatcccaattcacaatgcactgagggatgtggtcttaataggggaacaagcccgagctcaagatggcctgaagaagaggctggggaagctgaaggctacccttgagcaagcccaccaagccctggaggaggagaagaaaaagacagtagaccttctgtgctccatatttccctgtgaggttgctcagcagctgtggcaagggcaagttgtgcaagccaagaagttcagtaatgtcaccatgctcttctcagacatcgttgggttcactgccatctgctcccagtgctcaccgctgcaggtcatcaccatgctcaatgcactgtacactcgcttcgaccagcagtgtggagagctggatgtctacaaggtggagaccattggcgatgcctattgtgtagctgggggattacacaaagagagtgatactcatgctgttcagatagcgctgatggccgtgaagatgatggagctctctgatgaagttatgtctccccatggagaacctatcaagatgcgaattggactgcactctggatcagtttttgctggcgtcgttggagttaaaatgccccgttactgtctttttggaaacaatgtcactctggctaacaaatttgagtcctgcagtgtaccacgaaaaatcaatgtcagcccaacaacttacagattactcaaagactgtcctggtttcgtgtttacccctcgatcaagggaggaacttccaccaaacttccctagtgaaatccccggaatctgccattttctggatgcttaccaacaaggaacaaactcaaaaccatgcttccaaaagaaagatgtggaagatggcaatgccaattttttaggcaaagcatcaggaatagattag

Sequence Length

2073

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

NCBI and Uniprot Product Information

NCBI GI #

34190835

NCBI GeneID

2982

Molecular Weight

70,184 Da

NCBI Official Full Name

Homo sapiens guanylate cyclase 1, soluble, alpha 3, mRNA

NCBI Official Synonym Full Names

guanylate cyclase 1 soluble subunit alpha

NCBI Official Symbol

GUCY1A3

NCBI Official Synonym Symbols

GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A1

NCBI Protein Information

guanylate cyclase soluble subunit alpha-3

UniProt Protein Name

Guanylate cyclase soluble subunit alpha-3

Protein Family

Guanylate cyclase soluble

UniProt Gene Name

GUCY1A3

UniProt Synonym Gene Names

GUC1A3; GUCSA3; GUCY1A1; GCS-alpha-3

UniProt Entry Name

GCYA3_HUMAN

NCBI Description

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

GUCY1A3: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Protein type: Nucleotide Metabolism - purine; Lyase; EC 4.6.1.2; Receptor, misc.; Guanylyl cyclase

Chromosomal Location of Human Ortholog: 4q31.1-q31.2

Cellular Component: guanylate cyclase complex, soluble; plasma membrane

Molecular Function: adenylate cyclase activity; guanylate cyclase activity; protein binding; receptor activity

Biological Process: blood circulation; cGMP biosynthetic process

Disease: Moyamoya Disease 6 With Achalasia

Research Articles on GUCY1A3

1. Expression of the alpha1-A680T sGC variant in reporter cells resulted in higher cyclic guanosine monophosphate production compared with the wild-type enzyme and the purified alpha1-A680T sGC exhibited enhanced sensitivity to nitric oxide in vitro.

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Product Notes

The GUCY1A3 gucy1a3 (Catalog #AAA1276288) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgttctgca cgaagctcaa ggatctcaag atcacaggag agtgtccttt ctccttactg gcaccaggtc aagttcctaa cgagtcttca gaggaggcag caggaagctc agagagctgc aaagcaacca tgcccatctg tcaagacatt cctgagaaga acatacaaga aagtcttcct caaagaaaaa ccagtcggag ccgagtctat cttcacactt tggcagagag tatttgcaaa ctgattttcc cagagtttga acggctgaat gttgcacttc agagaacatt ggcaaagcac aaaataaaag aaagcaggaa atctttggaa agagaagact ttgaaaaaac aattgcagag caagcagttg cagcaggagt tccagtggag gttatcaaag aatctcttgg tgaagaggtt tttaaaatat gttacgagga agatgaaaac atccttgggg tggttggagg cacccttaaa gattttttaa acagcttcag tacccttctg aaacagagca gccattgcca agaagcagga aaaaggggca ggcttgagga cgcctccatt ctatgcctgg ataaggagga tgattttcta catgtttact acttcttccc taagagaacc acctccctga ttcttcccgg catcataaag gcagctgctc acgtattata tgaaacggaa gtggaagtgt cgttaatgcc tccctgcttc cataatgatt gcagcgagtt tgtgaatcag ccctacttgt tgtactccgt tcacatgaaa agcaccaagc catccctgtc ccccagcaaa ccccagtcct cgctggtgat tcccacatcg ctattctgca agacatttcc attccatttc atgtttgaca aagatatgac aattctgcaa tttggcaatg gcatcagaag gctgatgaac aggagagact ttcaaggaaa gcctaatttt gaagaatact ttgaaattct gactccaaaa atcaaccaga cgtttagcgg gatcatgact atgttgaata tgcagtttgt tgtacgagtg aggagatggg acaactctgt gaagaaatct tcaagggtta tggacctcaa aggccaaatg atctacattg ttgaatccag tgcaatcttg tttttggggt caccctgtgt ggacagatta gaagatttta caggacgagg gctctacctc tcagacatcc caattcacaa tgcactgagg gatgtggtct taatagggga acaagcccga gctcaagatg gcctgaagaa gaggctgggg aagctgaagg ctacccttga gcaagcccac caagccctgg aggaggagaa gaaaaagaca gtagaccttc tgtgctccat atttccctgt gaggttgctc agcagctgtg gcaagggcaa gttgtgcaag ccaagaagtt cagtaatgtc accatgctct tctcagacat cgttgggttc actgccatct gctcccagtg ctcaccgctg caggtcatca ccatgctcaa tgcactgtac actcgcttcg accagcagtg tggagagctg gatgtctaca aggtggagac cattggcgat gcctattgtg tagctggggg attacacaaa gagagtgata ctcatgctgt tcagatagcg ctgatggccg tgaagatgat ggagctctct gatgaagtta tgtctcccca tggagaacct atcaagatgc gaattggact gcactctgga tcagtttttg ctggcgtcgt tggagttaaa atgccccgtt actgtctttt tggaaacaat gtcactctgg ctaacaaatt tgagtcctgc agtgtaccac gaaaaatcaa tgtcagccca acaacttaca gattactcaa agactgtcct ggtttcgtgt ttacccctcg atcaagggag gaacttccac caaacttccc tagtgaaatc cccggaatct gccattttct ggatgcttac caacaaggaa caaactcaaa accatgcttc caaaagaaag atgtggaaga tggcaatgcc aattttttag gcaaagcatc aggaatagat tag. It is sometimes possible for the material contained within the vial of "GUCY1A3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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GUCY1A3 cdna clone