POP1 cdna clone
POP1 cDNA Clone
Synonyms
POP1; POP1 cDNA Clone; POP1 cdna clone
Sequence
atgtcaaatgcaaaagaaagaaaacacgccaagaaaatgagaaaccagcctaccaatgtgactctgtcctctggctttgtggctgacagaggtgtaaagcaccacagtggaggtgaaaaacctttccaagctcaaaaacaagagcctcatcctggaacttcacgacagcggcaaaccagagtcaacccccattctctgcctgaccctgaagtgaatgagcagtcttcctccaaagggatgtttagaaaaaagggaggatggaaagcaggtcccgagggcacgtctcaggagatccccaagtatataactgcttctacttttgctcaagcacgagctgctgaaatcagtgctatgttaaaagctgtgacccagaagtcttcgaattcactggtttttcagactctgccacggcacatgcgacgaagagccatgagccacaacgtcaaacgccttcccagacggttacaggagattgcccagaaagaggcggagaaagccgtacatcagaaaaaagaacattcaaaaaataaatgccataaagctcgaagatgtcacatgaaccggacgctagaatttaaccgtagacaaaagaagaacatttggttagaaactcacatctggcacgccaagcggtttcatatggtcaagaagtggggctactgccttggggagaggccaacagtcaagagccacagagcctgctatcgagccatgacgaaccggtgcctcctgcaggatttatcctattactgttgtttggagttgaaaggcaaagaggaagaaatactaaaggcgctttctggaatgtgtaacatagacacagggctgacgtttgcagcagttcactgcttgtctggaaagcgccaagggagccttgtgctttatcgggtgaataaatatcccagagaaatgcttgggcctgttacgtttatctggaagtcccagaggaccccgggtgacccttctgagagcaggcagctgtggatctggctgcatccaacccttaaacaggatatcttagaggaaataaaagcagcgtgccagtgtgtggaacccatcaaatcagctgtctgcatcgctgacccacttccaacaccatcccaagaaaaaagccaaactgaattgcctgacgagaaaattggcaagaaaagaaaaaggaaagatgatggagaaaatgctaaaccaattaaaaaaattatcggtgatggaactagagatccatgtctaccatactcttggatctctccaaccacaggcattataatcagcgatttgacgatggagatgaacagattccggctgattgggccactttcccactccatcctaactgaagcaataaaagctgcttctgtccacactgtgggagaggacacagaggagacacctcaccgctggtggatagaaacctgtaagaaacctgacagcgtttcccttcattgcagacaagaagccattttcgagttgttgggaggaataacatcaccagcagaaattccggcaggtactattctgggactgacagttggggatcctcgaataaatttgccccaaaagaagtccaacgctttgcccaatccagaaaaatgccaagataatgagaaagttagacagctgcttctggagggtgtgcctgtggaatgtacgcatagctttatctggaaccaagatatctgtaagagtgtcacagagaataaaatctcggatcaggatttaaaccggatgaggagtgaattgctggtgcctgggtcacagcttattttaggtccccatgaatccaagatacctatacttttgattcagcagccaggaaaagtgactggtgaagatcgactaggctggggaagtggctgggatgtcctactcccaaagggctggggcatggctttctggattccatttatttatcgaggtgtgagagtcggagggttgaaagagtctgcagtgcattctcagtataagaggtcgcctaatgtcccaggcgattttccagactgccctgccgggatgctgtttgcggaagagcaagctaagaatcttcttgaaaagtacaaaagacgccctcctgcaaaacggcccaactacgttaagcttggcactctggcacctttctgctgtccctgggagcagttaactcaagactgggagtcaagagtccaggcttacgaagaaccttctgtagcttcatctccaaatggtaaggagagtgacctaagaagatctgaggtgccttgtgctcccatgcctaaaaaaactcatcagccatctgatgaagtgggcacatccatagagcaccccagggaggcagaggaggtaatggatgcagggtgtcaagaatcggcagggcctgagaggatcacagaccaggaggccagtgaaaaccatgttgctgccacagggagtcacctctgcgttctcaggagtagaaaattactgaagcaactgtcagcctggtgtgggcccagttctgaggatagtcggggaggccggcgagctcccggcagaggccagcaaggattgaccagagaggcttgcctgtccatcttgggccacttccccagggccctggtttgggtcagcctgtccctgctcagcaagggcagccccgagcctcacaccatgatctgtgtcccagccaaggaggacttcctccagctccatgaggactggcattactgtgggccccaggaatccaaacacagtgacccattcaggagcaagatcctgaaacagaaagagaagaagaaaagggagaagaggcagaagccaggacgtgcctcttctgatggcccggcgggggaagagcccgtggctgggcaggaagctctgactctagggctgtggtcaggccctctgccgcgtgtgacgttgcactgctccagaactctcctaggctttgtgactcagggagatttttccatggctgttggctgtggagaagccctggggtttgttagcttgacaggcttgctggatatggtgtccagccagcctgcagcgcagaggggcttagtgctactgaggcctcccgcctctctgcagtatcgatttgcgaggattgctattgaggtgtga
Sequence Length
3075
Vector
pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
114,709 Da
NCBI Official Full Name
Homo sapiens processing of 1, ribonuclease P/MRP subunit (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
POP1 homolog, ribonuclease P/MRP subunit
NCBI Official Symbol
POP1
NCBI Protein Information
ribonucleases P/MRP protein subunit POP1
UniProt Protein Name
Ribonucleases P/MRP protein subunit POP1
Protein Family
UniProt Gene Name
POP1
UniProt Synonym Gene Names
KIAA0061; hPOP1
UniProt Entry Name
POP1_HUMAN
NCBI Description
This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Uniprot Description
POP1: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP. Defects in POP1 may be the cause of a severe skeletal dysplasia reminiscent of anauxetic dysplasia. Affected individuals show severe growth retardation of prenatal onset, a bone dysplasia affecting the epiphyses and metaphyses of the long bones particularly in the lower limbs, and abnormalities of the spine including irregularly shaped vertebral bodies and marked cervical spine instability.
Protein type: Ribonuclease; RNA processing; EC 3.1.26.5; Nucleolus
Chromosomal Location of Human Ortholog: 8q22.1
Cellular Component: extracellular space; nucleolar ribonuclease P complex; nucleoplasm; ribonuclease MRP complex
Molecular Function: protein binding; ribonuclease MRP activity; ribonuclease P activity
Biological Process: tRNA 5'-leader removal; tRNA catabolic process; tRNA processing
Research Articles on POP1
Similar Products
Product Notes
The POP1 pop1 (Catalog #AAA1276110) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtcaaatg caaaagaaag aaaacacgcc aagaaaatga gaaaccagcc taccaatgtg actctgtcct ctggctttgt ggctgacaga ggtgtaaagc accacagtgg aggtgaaaaa cctttccaag ctcaaaaaca agagcctcat cctggaactt cacgacagcg gcaaaccaga gtcaaccccc attctctgcc tgaccctgaa gtgaatgagc agtcttcctc caaagggatg tttagaaaaa agggaggatg gaaagcaggt cccgagggca cgtctcagga gatccccaag tatataactg cttctacttt tgctcaagca cgagctgctg aaatcagtgc tatgttaaaa gctgtgaccc agaagtcttc gaattcactg gtttttcaga ctctgccacg gcacatgcga cgaagagcca tgagccacaa cgtcaaacgc cttcccagac ggttacagga gattgcccag aaagaggcgg agaaagccgt acatcagaaa aaagaacatt caaaaaataa atgccataaa gctcgaagat gtcacatgaa ccggacgcta gaatttaacc gtagacaaaa gaagaacatt tggttagaaa ctcacatctg gcacgccaag cggtttcata tggtcaagaa gtggggctac tgccttgggg agaggccaac agtcaagagc cacagagcct gctatcgagc catgacgaac cggtgcctcc tgcaggattt atcctattac tgttgtttgg agttgaaagg caaagaggaa gaaatactaa aggcgctttc tggaatgtgt aacatagaca cagggctgac gtttgcagca gttcactgct tgtctggaaa gcgccaaggg agccttgtgc tttatcgggt gaataaatat cccagagaaa tgcttgggcc tgttacgttt atctggaagt cccagaggac cccgggtgac ccttctgaga gcaggcagct gtggatctgg ctgcatccaa cccttaaaca ggatatctta gaggaaataa aagcagcgtg ccagtgtgtg gaacccatca aatcagctgt ctgcatcgct gacccacttc caacaccatc ccaagaaaaa agccaaactg aattgcctga cgagaaaatt ggcaagaaaa gaaaaaggaa agatgatgga gaaaatgcta aaccaattaa aaaaattatc ggtgatggaa ctagagatcc atgtctacca tactcttgga tctctccaac cacaggcatt ataatcagcg atttgacgat ggagatgaac agattccggc tgattgggcc actttcccac tccatcctaa ctgaagcaat aaaagctgct tctgtccaca ctgtgggaga ggacacagag gagacacctc accgctggtg gatagaaacc tgtaagaaac ctgacagcgt ttcccttcat tgcagacaag aagccatttt cgagttgttg ggaggaataa catcaccagc agaaattccg gcaggtacta ttctgggact gacagttggg gatcctcgaa taaatttgcc ccaaaagaag tccaacgctt tgcccaatcc agaaaaatgc caagataatg agaaagttag acagctgctt ctggagggtg tgcctgtgga atgtacgcat agctttatct ggaaccaaga tatctgtaag agtgtcacag agaataaaat ctcggatcag gatttaaacc ggatgaggag tgaattgctg gtgcctgggt cacagcttat tttaggtccc catgaatcca agatacctat acttttgatt cagcagccag gaaaagtgac tggtgaagat cgactaggct ggggaagtgg ctgggatgtc ctactcccaa agggctgggg catggctttc tggattccat ttatttatcg aggtgtgaga gtcggagggt tgaaagagtc tgcagtgcat tctcagtata agaggtcgcc taatgtccca ggcgattttc cagactgccc tgccgggatg ctgtttgcgg aagagcaagc taagaatctt cttgaaaagt acaaaagacg ccctcctgca aaacggccca actacgttaa gcttggcact ctggcacctt tctgctgtcc ctgggagcag ttaactcaag actgggagtc aagagtccag gcttacgaag aaccttctgt agcttcatct ccaaatggta aggagagtga cctaagaaga tctgaggtgc cttgtgctcc catgcctaaa aaaactcatc agccatctga tgaagtgggc acatccatag agcaccccag ggaggcagag gaggtaatgg atgcagggtg tcaagaatcg gcagggcctg agaggatcac agaccaggag gccagtgaaa accatgttgc tgccacaggg agtcacctct gcgttctcag gagtagaaaa ttactgaagc aactgtcagc ctggtgtggg cccagttctg aggatagtcg gggaggccgg cgagctcccg gcagaggcca gcaaggattg accagagagg cttgcctgtc catcttgggc cacttcccca gggccctggt ttgggtcagc ctgtccctgc tcagcaaggg cagccccgag cctcacacca tgatctgtgt cccagccaag gaggacttcc tccagctcca tgaggactgg cattactgtg ggccccagga atccaaacac agtgacccat tcaggagcaa gatcctgaaa cagaaagaga agaagaaaag ggagaagagg cagaagccag gacgtgcctc ttctgatggc ccggcggggg aagagcccgt ggctgggcag gaagctctga ctctagggct gtggtcaggc cctctgccgc gtgtgacgtt gcactgctcc agaactctcc taggctttgt gactcaggga gatttttcca tggctgttgg ctgtggagaa gccctggggt ttgttagctt gacaggcttg ctggatatgg tgtccagcca gcctgcagcg cagaggggct tagtgctact gaggcctccc gcctctctgc agtatcgatt tgcgaggatt gctattgagg tgtga. It is sometimes possible for the material contained within the vial of "POP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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