PPP2R3C cdna clone
PPP2R3C cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Uniprot Description
PPP2R3C: May regulate MCM3AP phosphorylation through phosphatase recruitment. May play a role in the activation-induced cell death of B-cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 14q13.2
Cellular Component: centrosome; spindle
Molecular Function: protein binding
Biological Process: B cell homeostasis; cortical cytoskeleton organization and biogenesis; microtubule cytoskeleton organization and biogenesis; positive regulation of B cell differentiation; T cell homeostasis
Research Articles on PPP2R3C
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Product Notes
The PPP2R3C ppp2r3c (Catalog #AAA1275532) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgattggag aggaagcgat gatcaattac gaaaactttt tgaaggttgg tgaaaaggct ggagcaaagt gcaagcaatt tttcacagca aaagtctttg ctaaactcct tcatacagat tcatatggaa gaatttccat catgcagttc tttaattatg tcatgagaaa agtttggctt catcaaacaa gaataggact cagtttatat gatgtcgctg ggcaggggta ccttcgggaa tctgatttag aaaactacat attggaactt atccctacgt tgccacaatt agatggtctg gaaaaatctt tctactcctt ttatgtttgt acagcagtta ggaagttctt cttcttttta gatcctttaa gaacaggaaa gataaaaatt caagatattt tagcatgcag cttcctagat gatttattgg agctaaggga tgaggaactg tccaaggaga gtcaagaaac aaattggttt tctgctcctt ctgccctaag agtttatggc cagtacttga atcttgataa agatcacaat ggcatgctca gtaaagaaga actctcacgc tatggaacag ctaccatgac caatgtcttc ttagaccgtg ttttccagga gtgtctcact tatgatggag aaatggacta taagacctac ttggactttg tccttgcatt agaaaacaga aaggaacctg cagctctaca atatattttc aaactgcttg atattgagaa caaaggatac ctgaatgtct tttcacttaa ttatttcttt agggccatac aggaactaat gaaaatccat ggacaagatc ctgtttcatt tcaagatgtc aaggatgaaa tctttgacat ggtaaaacca aaggatcctt tgaaaatctc tcttcaggat ttaatcaaca gtaatcaagg agacacagta accaccattc taatcgattt gaatggcttc tggacttacg agaacagaga ggctcttgtt gcaaatgaca gtgaaaactc tgcagacctt gatgatacat ga. It is sometimes possible for the material contained within the vial of "PPP2R3C, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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