SEMA4C cdna clone

SEMA4C cDNA Clone

Gene Names

SEMA4C; SEMAF; SEMAI; SEMACL1; M-SEMA-F

Synonyms

SEMA4C; SEMA4C cDNA Clone; SEMA4C cdna clone

Ordering
Cat. Num. AAA1275208 For Research Use Only!

Sequence

ATGGCCCCACACTGGGCTGTCTGGCTGCTGGCAGCAAGGCTGTGGGGCCTGGGCATTGGGGCTGAGGTGTGGTGGAACCTTGTGCCGCGTAAGACAGTGTCTTCTGGGGAGCTGGCCACGGTAGTACGGCGGTTCTCCCAGACCGGCATCCAGGACTTCCTGACACTGACGCTGACGGAGCCCACTGGGCTTCTGTACGTGGGCGCCCGAGAGGCCCTGTTTGCCTTCAGCATGGAGGCCCTGGAGCTGCAAGGAGCGATCTCCTGGGAGGCCCCCGTGGAGAAGAAGACTGAGTGTATCCAGAAAGGGAAGAACAACCAGACCGAGTGCTTCAACTTCATCCGCTTCCTGCAGCCCTACAATGCCTCCCACCTGTACGTCTGTGGCACCTACGCCTTCCAGCCCAAGTGCACCTACGTCAACATGCTCACCTTCACTTTGGAGCATGGAGAGTTTGAAGATGGGAAGGGCAAGTGTCCCTATGACCCAGCTAAGGGCCATGCTGGCCTTCTTGTGGATGGTGAGCTGTACTCGGCCACACTCAACAACTTCCTGGGCACGGAACCCATTATCCTGCGTAACATGGGGCCCCACCACTCCATGAAGACAGAGTACCTGGCCTTTTGGCTCAACGAACCTCACTTTGTAGGCTCTGCCTATGTACCTGAGAGTGTGGGCAGCTTCACGGGGGACGACGACAAGGTCTACTTCTTCTTCAGGGAGCGGGCAGTGGAGTCCGACTGCTATGCCGAGCAGGTGGTGGCTCGTGTGGCCCGTGTCTGCAAGGGCGATATGGGGGGCGCACGGACCCTGCAGAGGAAGTGGACCACGTTCCTGAAGGCGCGGCTGGCATGCTCTGCCCCGAACTGGCAGCTCTACTTCAACCAGCTGCAGGCGATGCACACCCTGCAGGACACCTCCTGGCACAACACCACCTTCTTTGGGGTTTTTCAAGCACAGTGGGGTGACATGTACCTGTCGGCCATCTGTGAGTACCAGTTGGAAGAGATCCAGCGGGTGTTTGAGGGCCCCTATAAGGAGTACCATGAGGAAGCCCAGAAGTGGGACCGCTACACTGACCCTGTACCCAGCCCTCGGCCTGGCTCGTGCATTAACAACTGGCATCGGCGCCACGGCTACACCAGCTCCCTGGAGCTACCCGACAACATCCTCAACTTCGTCAAGAAGCACCCGCTGATGGAGGAGCAGGTGGGGCCTCGGTGGAGCCGCCCCCTGCTCGTGAAGAAGGGCACCAACTTCACCCACCTGGTGGCCGACCGGGTTACAGGACTTGATGGAGCCACCTATACAGTGCTGTTCATTGGCACAGGAGACGGCTGGCTGCTCAAGGCTGTGAGCCTGGGGCCCTGGGTTCACCTGATTGAGGAGCTGCAGCTGTTTGACCAGGAGCCCATGAGAAGCCTGGTGCTATCTCAGAGCAAGAAGCTGCTCTTTGCCGGCTCCCGCTCTCAGCTGGTGCAGCTGCCCGTGGCCGACTGCATGAAGTATCGCTCCTGTGCAGACTGTGTCCTCGCCCGGGACCCCTATTGCGCCTGGAGCGTCAACACCAGCCGCTGTGTGGCCGTGGGTGGCCACTCTGGATCTCTACTGATCCAGCATGTGATGACCTCGGACACTTCAGGCATCTGCAACCTCCGTGGCAGTAAGAAAGTCAGGCCCACTCCCAAAAACATCACGGTGGTGGCGGGCACAGACCTGGTGCTGCCCTGCCACCTCTCCTCCAACTTGGCCCATGCCCGCTGGACCTTTGGGGGCCGGGACCTGCCTGCGGAACAGCCCGGGTCCTTCCTCTACGATGCCCGGCTCCAGGCCCTGGTTGTGATGGCTGCCCAGCCCCGCCATGCCGGGGCCTACCACTGCTTTTCAGAGGAGCAGGGGGCGCGGCTGGCTGCTGAAGGCTACCTTGTGGCTGTCGTGGCAGGCCCGTCGGTGACCTTGGAGGCCCGGGCCCCCCTGGAAAACCTGGGGCTGGTGTGGCTGGCGGTGGTGGCCCTGGGGGCTGTGTGCCTGGTGCTGCTGCTGCTGGTGCTGTCATTGCGCCGGCGGCTGCGGGAAGAGCTGGAGAAAGGGGCCAAGGCTACTGAGAGGACCTTGGTGTACCCCCTGGAGCTGCCCAAGGAGCCCACCAGTCCCCCCTTCCGGCCCTGTCCTGAACCAGATGAGAAACTTTGGGATCCTGTCGGTTACTACTATTCAGATGGCTCCCTTAAGATAGTACCTGGGCATGCCCGGTGCCAGCCCGGTGGGGGGCCCCCTTCGCCACCTCCAGGCATCCCAGGCCAGCCTCTGCCTTCTCCAACTCGGCTTCACCTGGGGGGTGGGCGGAACTCAAATGCCAATGGTTACGTGCGCTTACAACTAGGAGGGGAGGACCGGGGAGGGCTCGGGCACCCCCTGCCTGAGCTCGCGGATGAACTGAGACGCAAACTGCAGCAACGCCAGCCACTGCCCGACTCCAACCCCGAGGAGTCATCAGTATGA

Sequence Length

2502

Vector

Please Inquire

NCBI and Uniprot Product Information

NCBI GI #

80478938

NCBI GeneID

54910

Molecular Weight

92,623 Da

NCBI Official Full Name

Homo sapiens sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C, mRNA

NCBI Official Synonym Full Names

semaphorin 4C

NCBI Official Symbol

SEMA4C

NCBI Official Synonym Symbols

SEMAF; SEMAI; SEMACL1; M-SEMA-F

NCBI Protein Information

semaphorin-4C

UniProt Protein Name

Semaphorin-4C

Protein Family

Semaphorin

UniProt Gene Name

SEMA4C

UniProt Synonym Gene Names

KIAA1739; SEMAI

UniProt Entry Name

SEM4C_HUMAN

Uniprot Description

SEMA4C: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. Belongs to the semaphorin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: extracellular space; membrane; postsynaptic density; synaptic vesicle membrane

Molecular Function: chemorepellent activity; protein binding; semaphorin receptor binding

Biological Process: cell migration in hindbrain; muscle cell differentiation; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; neural tube closure; positive regulation of cell migration; positive regulation of stress-activated MAPK cascade

Research Articles on SEMA4C

1. Suggest that up-regulation of miR-125b or targeting Sema4C could serve as novel approaches to reverse chemotherapy resistance in breast cancers.

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Product Notes

The SEMA4C sema4c (Catalog #AAA1275208) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCCCCAC ACTGGGCTGT CTGGCTGCTG GCAGCAAGGC TGTGGGGCCT GGGCATTGGG GCTGAGGTGT GGTGGAACCT TGTGCCGCGT AAGACAGTGT CTTCTGGGGA GCTGGCCACG GTAGTACGGC GGTTCTCCCA GACCGGCATC CAGGACTTCC TGACACTGAC GCTGACGGAG CCCACTGGGC TTCTGTACGT GGGCGCCCGA GAGGCCCTGT TTGCCTTCAG CATGGAGGCC CTGGAGCTGC AAGGAGCGAT CTCCTGGGAG GCCCCCGTGG AGAAGAAGAC TGAGTGTATC CAGAAAGGGA AGAACAACCA GACCGAGTGC TTCAACTTCA TCCGCTTCCT GCAGCCCTAC AATGCCTCCC ACCTGTACGT CTGTGGCACC TACGCCTTCC AGCCCAAGTG CACCTACGTC AACATGCTCA CCTTCACTTT GGAGCATGGA GAGTTTGAAG ATGGGAAGGG CAAGTGTCCC TATGACCCAG CTAAGGGCCA TGCTGGCCTT CTTGTGGATG GTGAGCTGTA CTCGGCCACA CTCAACAACT TCCTGGGCAC GGAACCCATT ATCCTGCGTA ACATGGGGCC CCACCACTCC ATGAAGACAG AGTACCTGGC CTTTTGGCTC AACGAACCTC ACTTTGTAGG CTCTGCCTAT GTACCTGAGA GTGTGGGCAG CTTCACGGGG GACGACGACA AGGTCTACTT CTTCTTCAGG GAGCGGGCAG TGGAGTCCGA CTGCTATGCC GAGCAGGTGG TGGCTCGTGT GGCCCGTGTC TGCAAGGGCG ATATGGGGGG CGCACGGACC CTGCAGAGGA AGTGGACCAC GTTCCTGAAG GCGCGGCTGG CATGCTCTGC CCCGAACTGG CAGCTCTACT TCAACCAGCT GCAGGCGATG CACACCCTGC AGGACACCTC CTGGCACAAC ACCACCTTCT TTGGGGTTTT TCAAGCACAG TGGGGTGACA TGTACCTGTC GGCCATCTGT GAGTACCAGT TGGAAGAGAT CCAGCGGGTG TTTGAGGGCC CCTATAAGGA GTACCATGAG GAAGCCCAGA AGTGGGACCG CTACACTGAC CCTGTACCCA GCCCTCGGCC TGGCTCGTGC ATTAACAACT GGCATCGGCG CCACGGCTAC ACCAGCTCCC TGGAGCTACC CGACAACATC CTCAACTTCG TCAAGAAGCA CCCGCTGATG GAGGAGCAGG TGGGGCCTCG GTGGAGCCGC CCCCTGCTCG TGAAGAAGGG CACCAACTTC ACCCACCTGG TGGCCGACCG GGTTACAGGA CTTGATGGAG CCACCTATAC AGTGCTGTTC ATTGGCACAG GAGACGGCTG GCTGCTCAAG GCTGTGAGCC TGGGGCCCTG GGTTCACCTG ATTGAGGAGC TGCAGCTGTT TGACCAGGAG CCCATGAGAA GCCTGGTGCT ATCTCAGAGC AAGAAGCTGC TCTTTGCCGG CTCCCGCTCT CAGCTGGTGC AGCTGCCCGT GGCCGACTGC ATGAAGTATC GCTCCTGTGC AGACTGTGTC CTCGCCCGGG ACCCCTATTG CGCCTGGAGC GTCAACACCA GCCGCTGTGT GGCCGTGGGT GGCCACTCTG GATCTCTACT GATCCAGCAT GTGATGACCT CGGACACTTC AGGCATCTGC AACCTCCGTG GCAGTAAGAA AGTCAGGCCC ACTCCCAAAA ACATCACGGT GGTGGCGGGC ACAGACCTGG TGCTGCCCTG CCACCTCTCC TCCAACTTGG CCCATGCCCG CTGGACCTTT GGGGGCCGGG ACCTGCCTGC GGAACAGCCC GGGTCCTTCC TCTACGATGC CCGGCTCCAG GCCCTGGTTG TGATGGCTGC CCAGCCCCGC CATGCCGGGG CCTACCACTG CTTTTCAGAG GAGCAGGGGG CGCGGCTGGC TGCTGAAGGC TACCTTGTGG CTGTCGTGGC AGGCCCGTCG GTGACCTTGG AGGCCCGGGC CCCCCTGGAA AACCTGGGGC TGGTGTGGCT GGCGGTGGTG GCCCTGGGGG CTGTGTGCCT GGTGCTGCTG CTGCTGGTGC TGTCATTGCG CCGGCGGCTG CGGGAAGAGC TGGAGAAAGG GGCCAAGGCT ACTGAGAGGA CCTTGGTGTA CCCCCTGGAG CTGCCCAAGG AGCCCACCAG TCCCCCCTTC CGGCCCTGTC CTGAACCAGA TGAGAAACTT TGGGATCCTG TCGGTTACTA CTATTCAGAT GGCTCCCTTA AGATAGTACC TGGGCATGCC CGGTGCCAGC CCGGTGGGGG GCCCCCTTCG CCACCTCCAG GCATCCCAGG CCAGCCTCTG CCTTCTCCAA CTCGGCTTCA CCTGGGGGGT GGGCGGAACT CAAATGCCAA TGGTTACGTG CGCTTACAAC TAGGAGGGGA GGACCGGGGA GGGCTCGGGC ACCCCCTGCC TGAGCTCGCG GATGAACTGA GACGCAAACT GCAGCAACGC CAGCCACTGC CCGACTCCAA CCCCGAGGAG TCATCAGTAT GA. It is sometimes possible for the material contained within the vial of "SEMA4C, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

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SEMA4C cdna clone