WDR7 cdna clone
WDR7 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
WDR7: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Two alternatively spliced human isoforms have been described.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 18q21.31
Cellular Component: cytoplasm
Research Articles on WDR7
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Product Notes
The WDR7 wdr7 (Catalog #AAA1274012) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCAGGAA ACAGCCTTGT TCTACCCATT GTTCTTTGGG GTCGAAAAGC GCCCACACAT TGCATCTCAG CGGTACTTTT AACAGATGAT GGGGCCACGA TCGTAACAGG ATGTCACGAC GGACAAATAT GTCTCTGGGA TCTTTCAGTA GAACTGCAAA TTAATCCTCG AGCACTGTTG TTTGGTCATA CAGCAGTTCT CTTCCAACAA GTGAAAGAAA CGATCAAAGA GAACATCAAG GAACACCTCC TTGATGATGA AGAGGAGGAT GAGGAGATAA TGAGGCAGAG AAGGGAAGAA AGTGATCCTG AATATCGGTC CAGCAAATCA AAGCCATTGA CCCTATTAGA ATATAATTTA ACTATGGACA CTGCAAAGCT GTTTATGTCC TGCCTTCACG CCTGGGGTTT GAATGAAGTA CTGGATGAAG TTTGCCTGGA TCGCCTTGGA ATGCTGAAAC CCCACTGCAC CGTATCGTTT GGCCTCTTGT CAAGAGGAGG CCATATGTCA CTGATGCTGC CGGGTTATAA TCAGCCTGCT TGTAAACTGT CACATGGGAA AACAGAAGTA GGAAGGAAGC TGCCAGCGTC TGAGGGAGTA GGAAAGGGAA CTTACGGAGT GTCCCGTGCC GTCACCACAC AGCATCTCCT GTCTATCATT TCTTTGGCAA ATACTTTAAT GAGTATGACC AATGCAACTT TTATTGGTGA TCATATGAAG AAGGGTCCTA CCAGGCCACC TAGACCAAGC ACCCCAGACC TTTCTAAGGC AAGGGGTTCC CCTCCAACTT CCAGTAATAT TGTGCAAGGA CAGATTAAAC AAGTTGCTGC ACCTGTCGTT TCCGCTCGGT CTGATGCTGA TCACTCTGGC TCTGACCCTC CTTCTGCTCC TGCTTTACAT ACCTGTTTCT TAGTAAATGA AGGTTGGAGT CAGTTAGCTG CTATGCACTG TGTTATGCTG CCAGACCTAC TGGGATTGGA TAAATTTAGG CCTCCCCTTC TGGAGATGCT GGCCCGAAGA TGGCAAGATC GATGCTTGGA GGTGAGAGAA GCCGCGCAGG CCCTGCTTCT GGCGGAACTG AGAAGAATTG AGCAGGCAGG CAGGAAGGAA GCCATTGATG CCTGGGCTCC TTACTTACCT CAGTACATAG ACCACGTCAT ATCACCTGGA GTCACATCAG AAGCCGCGCA GACTATCACC ACGGCTCCTG ATGCCTCAGG GCCTGAAGCA AAAGTCCAGG AGGAAGAGCA TGACCTTGTT GACGATGACA TCACCACTGG TTGCTTATCA AGTGTCCCAC AAATGAAAAA AATTTCTACA TCTTACGAGG AAAGACGGAA GCAAGCTACC GCTATTGTTT TACTTGGAGT AATAGGAGCT GAATTTGGTG CTGAAATTGA ACCTCCTAAA CTATTGACCA GACCTCGAAG CTCTAGCCAA ATTCCTGAGG GATTCGGGTT GACTAGTGGT GGATCCAACT ACTCGCTGGC CAGACATACT TGCAAGGCAC TGACGTTTCT TCTGCTACAG CCTCCAAGCC CCAAACTTCC TCCACACAGC ACTATCCGAA GAACAGCCAT TGATCTGATT GGACGTGGGT TCACTGTTTG GGAGCCTTAC ATGGATGTGT CCGCTGTTCT GATGGGGCTT CTCGAACTTT GTGCCGATGC CGAGAAACAA CTTGCCAACA TCACAATGGG GTTGCCTCTG AGCCCAGCAG CTGACTCGGC CCGCTCTGCG AGGCATGCCC TCTCGCTCAT TGCCACCGCC AGACCACCCG CCTTCATCAC CACCATAGCC AAAGAGGTAC ACAGACATAC GGCTCTTGCA GCAAATACCC AATCACAGCA GAATATGCAC ACAACAACTC TTGCACGAGC TAAAGGGGAA ATTTTGAGAG TCATTGAAAT TCTTATTGAA AAGATGCCCA CAGATGTTGT GGATCTTCTT GTGGAGGTTA TGGACATCAT TATGTACTGC CTTGAAGGAT CTTTAGTTAA AAAGAAAGGT CTTCAAGAAT GTTTCCCAGC CATCTGCAGG TTCTACATGG TCAGCTATTA TGAGCGGAAT CACAGAATAG CAGTTGGAGC TCGCCATGGT TCAGTGGCCC TGTACGACAT CCGGACTGGA AAATGTCAGA CAATCCATGG ACACAAGGGA CCAATCACTG CAGTGGCTTT TGCTCCTGAT GGAAGATATC TTGCCACCTA CTCAAACACT GACAGCCACA TTTCTTTTTG GCAGATGAAC ACGTCACTGC TGGGAAGCAT CGGCATGCTG AACTCGGCAC CTCAGCTGCG CTGCATTAAA ACCTACCAGG TGCCCCCTGT GCAGCCCGCG TCCCCCGGCT CCCACAATGC CCTCAAGCTT GCCCGGCTCA TCTGGACTTC CAACCGCAAC GTCATCCTCA TGGCCCATGA CGGGAAGGAG CACCGCTTCA TGGTCTAA. It is sometimes possible for the material contained within the vial of "WDR7, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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