Rabbit anti-Human, Rat WDR7 Polyclonal Antibody | anti-WDR7 antibody

WDR7 Rabbit Polyclonal

Cat. Num. AAA7605734

• Gene Names: WDR7; TRAG
• Reactivity: Human, Rat
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: WDR7; Polyclonal Antibody; WDR7 Rabbit Polyclonal; anti-WDR7 antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1457

• Applicable Applications for anti-WDR7 antibody: ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
• Immunogen: WD repeat domain 7
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis slide using MBS7605734 (WDR7 Antibody) at dilution of 1:50)

Western Blot (WB)

(rat brain tissue were subjected to SDS PAGE followed by western blot with MBS7605734 (WDR7 Antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 73747879
• NCBI GeneID: 23335
• NCBI Accession #: NP_443066.2
• NCBI GenBank Nucleotide #: NM_052834.2
• Molecular Weight: 160,510 Da
• NCBI Official Full Name: WD repeat-containing protein 7 isoform 2
• NCBI Official Synonym Full Names: WD repeat domain 7
• NCBI Official Symbol: WDR7
• NCBI Official Synonym Symbols: TRAG
• NCBI Protein Information: WD repeat-containing protein 7
• UniProt Protein Name: WD repeat-containing protein 7
• Protein Family: WD repeat-containing protein
• UniProt Gene Name: WDR7
• UniProt Synonym Gene Names: KIAA0541; TRAG
• UniProt Entry Name: WDR7_HUMAN

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

WDR7: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Two alternatively spliced human isoforms have been described.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 18q21.31

Cellular Component: cytoplasm; synaptic vesicle

Biological Process: hemopoietic progenitor cell differentiation