DBF4B cdna clone
DBF4B cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a regulator of the cell division cycle 7 homolog (S. cerevisiae) protein, a serine-threonine kinase which links cell cycle regulation to genome duplication. This protein localizes to the nucleus and, in complex with the cell division cycle 7 homolog (S. cerevisiae) protein, may facilitate M phase progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
Uniprot Description
DBF4B: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17q21.31|17q21
Cellular Component: cytoplasm; intracellular membrane-bound organelle; nuclear chromatin; nucleoplasm; nucleus
Molecular Function: protein binding; protein kinase activator activity; protein kinase binding
Biological Process: positive regulation of cell proliferation
Research Articles on DBF4B
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Product Notes
The DBF4B dbf4b (Catalog #AAA1273699) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagcgaac cgggaaaggg agacgattgc ctcgagctgg agagttccat ggctgagagt aggctccggg ccccggacct aggagtttcc aggtgtctag gaaaatgcca gaagaactca ccaggtgcca ggaagcatcc cttttccgga aagtcctttt acttggatct gcctgctggc aagaatctcc agtttttgac gggggccatt cagcaactgg gtggggtaat tgagggtttt ctgagcaaag aagtaagtta catcgtgtcc agccgcagag aagtaaaggc agagagcagt gggaaaagcc atagaggctg ccctagccct agccccagtg aggtcagagt ggaaacatcg gccatggttg atccaaaagg cagccacccc aggccttcac ggaaacccgt tgactcggtg cctctaagca gagggaagga gctgctgcag aaggctatca gaaaccaggg gagcatcagt ggaggaggca gtgggggcag cagcagcctc ctgaccaatg cccgctcttg gggagtgagg attctgcacg tggatgaaat gatgatgcac gtgcaacagc tgtctcttgc gtctttatgt gtgaaaaaac aacagccaaa gaagccagag ggaacatgtc cagcagcaga gtcaagaaca cggaaagtgg ccagactgaa ggccccgttc ctcaaaatcg aagatgaaag caggaagttt cgtcctttcc atcatcagtt taaatccttt cctgaaattt cttttcttgg acccaaagat gcaagtccct ttgaggcccc gacgaccctg ggcagcatgc accataccag agaatccaag gatggagagc caagcccacg atcagctgcc cacaccatgc ccaggaggaa gaaaggctac tgcgagtgct gtcaggaggc cttcgaggag ctccatgtgc atcttcagag tgcccagcac cggagctttg ccctggaagc ccatctatat gcagaagtgg acaggatcat tgctcagctc agccacagct ttgcagacat ccctttccag gctggcctcc ccaggtggtc aggttcccca gcttctgatt gtgaccctct ctgtcctgag actctgcacc cccatcagcc ctcccatccc agggcagcat ctcccaggat aaggaaagaa gacagctgcc aggcatcagt gacccaaggc agggctgcgg gccagcagcg atggacagaa tcactagatg gtgtgatggg acctcctgca agtcacacat gtcacaggcc ttgccgtctg ccctga. It is sometimes possible for the material contained within the vial of "DBF4B, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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