PXK cdna clone
PXK cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Description
Slob: Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity. Belongs to the protein kinase superfamily. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, Other; Other group; Slob family
Chromosomal Location of Human Ortholog: 3p14.3
Cellular Component: cytoplasm; microtubule organizing center; plasma membrane
Biological Process: inflammatory response; negative regulation of ATPase activity; negative regulation of ion transport; regulation of membrane potential; regulation of synaptic transmission
Research Articles on PXK
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Product Notes
The PXK pxk (Catalog #AAA1272251) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggccttca tggagaagcc gccagccggc aaggtgctgc tggacgacac ggtgccgctg acagcagcca tcgaggcgag ccagagcctg cagtcccaca cggaatatat tattcgagtg caaagaggaa tttctgtgga aaacagctgg cagattgtta gaagatacag tgactttgat ttgcttaaca acagcttaca gattgcaggc ctaagtctac ctcttcctcc caaaaaattg attggtaaca tggatcgtga attcatagct gaaaggcaga aaggtcttca gaactatctc aacgtgatca caacaaatca tatcttgtct aattgtgagc tggttaagaa gtttttagat ccaaacaact attccgcaaa ctatactgag attgccttgc aacaggtttc catgttcttc cgatcagaac caaagtggga ggtggtggaa cctttgaaag acataggttg gagaataagg aagaaatatt tcttgatgaa gattaaaaat cagccaaagg aacggctagt gttaagctgg gctgaccttg gcccagacaa gtatttgtca gataaagatt ttcagtgtct aatcaaactt ctgccttctt gtttgcaccc ttacatctat cgggttacct ttgccacagc taatgaatcc tcagcgttgc taattaggat gtttaacgaa aagggaacat tgaaggatct gatctacaag gcaaaaccaa aagacccatt tctaaagaag tactgcaacc ctaagaagat tcagggcctg gaactccagc aaataaaaac atatggacgg caaatattag aggtactgaa gtttcttcat gacaagggat tcccttatgg gcatcttcac gcctccaatg tgatgctcga tggggacact tgtcggctgc tggaccttga gaattcctta ttgggcctgc cttccttcta ccgatcttat ttttcacaat tcaggaaaat caatacattg gaaagtgtgg atgtccactg ctttggccac ttactgtatg aaatgactta tggacgaccg ccagactcgg tgcctgtgga ctccttccct cctgccccgt ccatggctgt ggtggccgtg ttggagtcta cgctgtcttg tgaagcctgt aaaaatggca tgcctaccat ctcccggctc ttacagatgc cattattcag cgatgtttta ctaaccactt ctgaaaaacc acagtttaag atccctacaa agttaaaaga ggcattgaga attgccaaag aatgtataga gaagagacta attgaggaac agaaacagat tcaccagcat cgaagactga caagagctca gtcccaccat tga. It is sometimes possible for the material contained within the vial of "PXK, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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