Western Blot (WB)
(Western Blot analysis of PXK expression in transfected 293T cell line by PXK polyclonal antibody. Lane 1: PXK transfected lysate (51.8kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human PXK Polyclonal Antibody | anti-PXK antibody
PXK (PX Domain-containing Protein Kinase-like Protein, Modulator of Na,K-ATPase, MONaKA)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of PXK expression in transfected 293T cell line by PXK polyclonal antibody. Lane 1: PXK transfected lysate (51.8kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PXK expression in transfected 293T cell line by PXK polyclonal antibody. Lane 1: PXK transfected lysate (51.8kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
PXK binds to the Na,K-ATPase beta-1 (ATP1B1; MIM 182330) and beta-3 (ATP1B3; MIM 601867) subunits and modulates both Na,K-ATPase enzymatic and ion pump activities (Mao et al., 2005 [PubMed 16135750]).[supplied by OMIM, Mar 2008]
Uniprot Description
Slob: Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity. Belongs to the protein kinase superfamily. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Kinase, protein; Other group; Slob family
Chromosomal Location of Human Ortholog: 3p14.3
Cellular Component: cytoplasm; plasma membrane; microtubule organizing center; nucleus
Molecular Function: protein C-terminus binding; nucleotide binding; actin binding; ATP binding; phosphoinositide binding; protein kinase activity
Biological Process: regulation of synaptic transmission; inflammatory response; protein amino acid phosphorylation; negative regulation of ion transport; negative regulation of ATPase activity
Research Articles on PXK
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Product Notes
The PXK pxk (Catalog #AAA6010113) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PXK (PX Domain-containing Protein Kinase-like Protein, Modulator of Na,K-ATPase, MONaKA) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PXK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the PXK pxk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAFMEKPPAG KVLLDDTVPL TAAIEASQSL QSHTEYIIRV QRGISVENSW QIVRRYSDFD LLNNSLQIAG LSLPLPPKKL IGNMDREFIA ERQKGLQNYL NVITTNHILS NCELVKKFLD PNNYSANYTE IALQQVSMFF RSEPKWEVVE PLKDIGWRIR KKYFLMKIKN QPKERLVLSW ADLGPDKYLS DKDFQCLIKL LPSCLHPYIY RVTFATANES SALLIRMFNE KGTLKDLIYK AKPKDPFLKK YCNPKKIQGL ELQQIKTYGR QILEVLKFLH DKGFPYGHLH ASNVMLDGDT CRLLDLENSL LGLPSFYRSY FSQFRKINTL ESVDVHCFGH LLYEMTYGRP PDSVPVDSFP PAPSMAVVAV LESTLSCEAC KNGMPTISRL LQMPLFSDVL LTTSEKPQFK IPTKLKEALR IAKECIEKRL IEEQKQIHQH RRLTRAQSHH. It is sometimes possible for the material contained within the vial of "PXK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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