CCNL2 cdna clone
CCNL2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
CCNL2: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis. Belongs to the cyclin family. Cyclin L subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription regulation; Cell cycle regulation
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: cyclin-dependent protein kinase holoenzyme complex; intracellular membrane-bound organelle; nucleoplasm; nucleus
Molecular Function: cyclin-dependent protein kinase regulator activity; protein binding
Biological Process: positive regulation of cyclin-dependent protein kinase activity; positive regulation of transcription from RNA polymerase II promoter
Research Articles on CCNL2
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Product Notes
The CCNL2 ccnl2 (Catalog #AAA1271692) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcggcgg cggcggcggc ggctggtgct gcagggtcgg cagctcccgc ggcagcggcc ggcgccccgg gatctggggg cgcaccctca gggtcgcagg gggtgctgat cggggacagg ctgtactccg gggtgctcat caccttggag aactgcctcc tgcctgacga caagctccgt ttcacgccgt ccatgtcgag cggcctcgac agcgacacag agaccgacct ccgcgtggtg ggctgcgagc tcatccaggc ggccggtatc ctgctccgcc tgccgcaggt ggccatggct accgggcagg tgttgttcca gcggttcttt tataccaagt ccttcgtgaa gcactccatg gagcatgtgt caatggcctg tgtccacctg gcttccaaga tagaagaggc cccaagacgc atacgggacg tcatcaatgt gtttcaccgc cttcgacagc tgagagacaa aaagaagccc gtgcctctac tactggatca agattatgtt aatttaaaga accaaattat aaaggcggaa agacgagttc tcaaagagtt gggtttctgc gtccatgtga agcatcctca taagataatc gttatgtacc ttcaggtgtt agagtgtgag cgtaaccaac acctggtcca gacctcatgg gtagcctctg agggtaagtg a. It is sometimes possible for the material contained within the vial of "CCNL2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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