Immunohistochemistry (IHC)
(Anti-CCNL2 / Cyclin L2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)
Rabbit anti-Human CCNL2 / Cyclin L2 Polyclonal Antibody | anti-CCNL2 antibody
Anti-CCNL2 / Cyclin L2 Antibody (aa345-374) IHC-plus
WB (1:1000)
For long term storage store at -20 degree C.
Immunohistochemistry (IHC)
(Anti-CCNL2 / Cyclin L2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)
Immunohistochemistry (IHC)
(Anti-CCNL2 / Cyclin L2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)
Western Blot (WB)
(CCNL2 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The CCNL2 antibody detected the CCNL2 protein (arrow).)
Western Blot (WB)
(CCNL2 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The CCNL2 antibody detected the CCNL2 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
CCNL2: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis. Belongs to the cyclin family. Cyclin L subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation; Transcription regulation
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: cyclin-dependent protein kinase holoenzyme complex; intracellular membrane-bound organelle; nuclear speck; nucleoplasm; nucleus
Molecular Function: cyclin-dependent protein kinase regulator activity; protein binding; protein kinase binding
Biological Process: positive regulation of cyclin-dependent protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on CCNL2
Similar Products
Product Notes
The CCNL2 ccnl2 (Catalog #AAA249869) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CCNL2 / Cyclin L2 Antibody (aa345-374) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCNL2 / Cyclin L2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:75) WB (1:1000). Researchers should empirically determine the suitability of the CCNL2 ccnl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCNL2 / Cyclin L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
