Rabbit anti-Human DNAJC30 Polyclonal Antibody | anti-DNAJC30 antibody

DNAJC30, CT (DNAJC30, WBSCR18, DnaJ homolog subfamily C member 30, Williams-Beuren syndrome chromosomal region 18 protein) (FITC)

Cat. Num. AAA6292842

• Gene Names: DNAJC30; WBSCR18
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: DNAJC30; Polyclonal Antibody; CT (DNAJC30; WBSCR18; DnaJ homolog subfamily C member 30; Williams-Beuren syndrome chromosomal region 18 protein) (FITC); Williams-Beuren syndrome chromosomal region 18 protein; anti-DNAJC30 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-DNAJC30 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: DNAJC30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the C-terminal region of human DNAJC30.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(DNAJC30 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DNAJC30 antibody detected the DNAJC30 protein (arrow).)

Related Product Information for anti-DNAJC30 antibody

This intronless gene encodes a member of the DNAJ molecular chaperone homology domain-containing protein family. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.

Product Categories/Family for anti-DNAJC30 antibody

Antibodies; Disease Markers

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Lehner, B., et al. Genome Res. 14(7):1315-1323(2004). Merla, G., et al. Hum. Genet. 110(5):429-438(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 22538497
• NCBI GeneID: 84277
• NCBI Accession #: NP_115693.2
• NCBI GenBank Nucleotide #: NM_032317.2
• UniProt Accession #: Q96LL9; Q9BSG8
• Molecular Weight: 25,961 Da
• NCBI Official Full Name: dnaJ homolog subfamily C member 30
• NCBI Official Synonym Full Names: DnaJ (Hsp40) homolog, subfamily C, member 30
• NCBI Official Symbol: DNAJC30
• NCBI Official Synonym Symbols: WBSCR18
• NCBI Protein Information: dnaJ homolog subfamily C member 30; Williams Beuren syndrome chromosome region 18; williams-Beuren syndrome chromosomal region 18 protein
• UniProt Protein Name: DnaJ homolog subfamily C member 30
• Protein Family: DnaJ homolog subfamily
• UniProt Gene Name: DNAJC30
• UniProt Synonym Gene Names: WBSCR18
• UniProt Entry Name: DJC30_HUMAN

Uniprot Description

Tissue specificity: Expressed in brain, heart, kidney, liver, lung, spleen, stomach and testis. Ref.1

Involvement in disease: DNAJC30 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.

Sequence similarities: Contains 1 J domain.