USO1 cdna clone
USO1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Uniprot Description
TAP: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. Belongs to the VDP/USO1/EDE1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Vesicle
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: cell-cell adherens junction; cytosol; endoplasmic reticulum; Golgi apparatus; Golgi membrane; Golgi stack; membrane; nucleolus; transport vesicle
Molecular Function: protein binding; protein transporter activity
Biological Process: COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; Golgi vesicle docking; intracellular protein transport; transcytosis
Research Articles on USO1
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Product Notes
The USO1 uso1 (Catalog #AAA1271322) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaatttcc tccgcggggt aatggggggt cagagtgccg gaccccagca cacagaagcc gagacgattc aaaagctttg tgacagagta gcttcatcta ctttattgga tgatcgaaga aatgctgttc gtgctctcaa atcattatct aagaaatacc gcttggaagt gggtatacaa gctatggaac atcttattca tgttttacaa acagatcgtt cagattctga aataataggt tatgctttgg acacactata taatataata tctaatgaag aagaagaagt agaagaaaat tccacaagac agagtgaaga tttgggaagc caatttacag aaattttcat taagcagcag gaaaatgtca ctcttctgtt atctttattg gaggagtttg atttccatgt ccgctggcct ggtgtgaagc ttcttacttc tcttttaaaa caactagggc ctcaggtgca acaaattatt ttagtcagtc ctatgggtgt ttcaagattg atggacttac tagcggattc cagggaagtt atacgtaatg atggcgtctt actactgcag gcactaacaa gaagcaatgg tgcaatccag aaaattgttg cttttgaaaa tgctttcgag agactactgg acattatttc agaggagggg aacagtgatg gaggtatagt agttgaagat tgtttgattt tgctccaaaa cttattaaaa aacaacaact ccaatcaaaa tttttttaaa gaaggctcat atattcaacg tatgaaacct tggtttgaag ttggagatga aaattctggc tggtctgcac agaaagtgac caatctacat ctaatgctac agcttgttcg tgtattggta tctcccacca accctcctgg tgctaccagt agctgccaga aggctatgtt ccagtgtggg ttattgcagc agctttgtac tatcctaatg gctactgggg ttcctgctga tatcctgact gagaccataa atactgtatc agaagttatt cgaggctgcc aagtaaacca agactacttt gcatctgtaa atgcaccttc aaacccacca agaccggcaa ttgtagtact tctcatgtcc atggttaatg aaaggcagcc atttgttttg cgctgtgctg ttctctattg tttccagtgt ttcttgtata aaaaccaaaa aggacaagga gaaatcgtgt caacactttt accttctacc attgatgcaa caggtaattc agtttcagct ggccagttat tatgtggagg tttgttttct actgattcac tttcaaactg gtgtgctgct gtggcccttg cccatgcgtt gcaagaaaat gccacccaga aagaacagtt gctcagggtt caacttgcta caagtattgg caaccctcca gtttctttac ttcaacagtg caccaatatt ctttcacagg gaagcaaaat acaaacaaga gttggattat taatgttgct ttgtacctgg ctaagcaatt gtcccattgc agtaacgcat tttcttcaca attcagccaa tgttccattc cttacaggac aaattgcaga aaatcttgga gaagaagagc agttggtcca aggcttatgt gcccttttgt tgggcatttc gatttatttc aatgataact cacttgagag ctacatgaaa gagaagctaa aacaactgat tgagaagagg attggcaaag agaatttcat agagaaacta ggatttatta gcaaacatga gttgtattcc agagcatctc agaaacccca gccaaacttt cccagtccag aatacatgat atttgatcat gagtttacga agctggtaaa agaacttgaa ggtgttataa ctaaggctat ttataagtcc agtgaagaag ataaaaaaga agaagaggtg aaaaaaacat tagaacagca tgacaatatt gtgactcact acaaaaatat gattcgagag caagatctcc aacttgagga attaaggcag caggtttcta cattaaaatg tcaaaatgaa cagctccaga cggcagtcac acagcaagta tcacagatcc agcagcacaa agaccagtat aatcttctta aaatacagct aggaaaagac aatcagcatc aaggttctta cagtgagggg gctcagatga atggcattca gccagaagaa attggtagat tgcgagaaga gatagaagaa ttaaaacgta atcaggaact tttacaaagc cagctgactg aaaaggactc tatgattgaa aatatgaaat cttcccaaac atctggcaca aatgaacagt cttcagcaat agtttcagct agagattctg aacaagttgc agaattaaaa caggaactgg caactttaaa gtctcagtta aactcacaat ctgtggagat caccaaacta cagacagaaa agcaggaact gttacagaaa acagaagcgt ttgcaaaatc agttgaggta caaggagaga ccgagactat aatagccacc aaaactactg atgtagaagg aagactgtca gcattattac aagagaccaa agagttaaag aatgaaatta aagctctgtc tgaggaaaga actgccatta aagagcagct ggattcatct aatagtacca ttgccatttt acaaactgag aaagacaaac tagagttgga aattacagat tctaaaaaag aacaagatga tctcttggtg ctcttggccg atcaagatca gaaaatactg tcattgaaga ataaactcaa ggatcttggt catccagttg aagaagagga tgaacttgaa tctggagacc aagaggatga ggatgatgaa agtgaagatc ctggcaagga tctagatcat atctag. It is sometimes possible for the material contained within the vial of "USO1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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