UBE2G1 cdna clone
UBE2G1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]
Uniprot Description
UBE2G1: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4. Belongs to the ubiquitin-conjugating enzyme family.
Protein type: EC 6.3.2.19; Ubiquitin conjugating system; Ubiquitin ligase; Ligase
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: cytoplasm
Molecular Function: ubiquitin protein ligase binding; ubiquitin-protein ligase activity
Biological Process: cellular protein catabolic process; ubiquitin-dependent protein catabolic process
Research Articles on UBE2G1
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Product Notes
The UBE2G1 ube2g1 (Catalog #AAA1270700) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgacggagc tgcagtcggc actgctactg cgaagacagc tggcagaact caacaaaaat ccagtggaag gcttttctgc aggtttaata gatgacaatg atctctaccg atgggaagtc cttattattg gccctccaga tacactttat gaaggtggtg tttttaaggc tcatcttact ttcccaaaag attatcccct ccgacctcct aaaatgaaat tcattacaga aatctggcac ccaaatgttg ataaaaatgg tgatgtgtgc atttctattc ttcatgagcc tggggaagat aagtatggtt atgaaaagcc agaggaacgc tggctcccta tccacactgt ggaaaccatc atgattagtg tcatttctat gctggcagac cctaatggag actcacctgc taatgttgat gctgcgaaag aatggaggga agatagaaat ggagaattta aaagaaaagt tgcccgctgt gtaagaaaaa gccaagagac tgcttttgag tga. It is sometimes possible for the material contained within the vial of "UBE2G1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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