SF3A1 cdna clone
SF3A1 cDNA Clone
Gene Names
SF3A1; PRP21; PRPF21; SAP114; SF3A120
Synonyms
SF3A1; SF3A1 cDNA Clone; SF3A1 cdna clone
Sequence
atgccggccggacccgtgcaggcggtgcccccgccgccgcccgtgcccacggagcccaaacagcccacagaagaagaagcatcttcaaaggaggattctgcaccttctaagccagttgtggggattatttaccctcctccagaggtcagaaatattgttgacaagactgccagctttgtggccagaaacgggcctgaatttgaagctaggatccgacagaacgagatcaacaaccccaagttcaactttctgaaccccaatgacccttaccatgcctactaccgccacaaggtcagcgagttcaaggaagggaaggctcaggagccgtccgccgccatccccaaggtcatgcagcagcagcagcagaccacccagcagcagctgccccagaaggtccaagcccaagtaatccaagagaccatcgtgcccaaagagcctcctcctgagtttgagttcattgctgatcctccctctatctcagccttcgacttggatgtggtgaagctgacggctcagtttgtggccaggaatgggcgccagtttctgacccagctgatgcagaaagagcagcgcaactaccagtttgactttctccgcccacagcacagcctcttcaactacttcacgaagctagtggaacagtacaccaagatcttgattccacccaaaggtttattttcaaagctcaagaaagaggctgaaaacccccgagaagttttggatcaggtgtgttaccgagtggaatgggccaaattccaggaacgtgagaggaagaaggaagaagaggagaaggagaaggagcgggtggcctatgctcagatcgactggcatgattttgtggtggtggaaacagtggacttccaacccaatgagcaagggaacttccctccccccaccacgccagaggagctgggggcccgaatcctcattcaggagcgctatgaaaagtttggggagagtgaggaagttgagatggaggtcgagtctgatgaggaggatgacaaacaggagaaggcggaggagcctccttcccagctggaccaggacacccaagtacaagatatggatgagggttcagatgatgaagaagaagggcagaaagtgcccccacccccagagacacccatgcctccacctctgcccccaactccagaccaagtcattgtccgcaaggattatgatcccaaagcctccaagcccttgcctccagcccctgctccagatgagtatcttgtgtcccccattactggggagaagatccccgccagcaaaatgcaggaacacatgcgcattggacttcttgaccctcgctggctggagcagcgggatcgctccatccgtgagaagcagagcgatgatgaggtgtacgcaccaggtctggatattgagagcagcttgaagcagttggctgagcggcgtactgacatcttcggtgtagaggaaacagccattggtaagaagatcggtgaggaggagatccagaagccagaggaaaaggtgacctgggatggccactcaggcagcatggcccggacccagcaggctgcccaggccaacatcaccctccaggagcagattgaggccattcacaaggccaaaggcctggtgccagaggatgacactaaagagaagattggccccagcaagcccaatgaaatccctcaacagccaccgccaccatcttcagccaccaacatccccagctcggctccacccatcacttcagtgccccgaccacccacaatgccacctccagttcgtactacagttgtctccgcagtacccgtcatgccccggcccccaatggcatctgtggtccggctgcccccaggctcagtgatcgcccccatgccgcccatcatccacgcgcccagaatcaacgtggtgcccatgcctccctcggcccctcctattatggccccccgcccaccccccatgattgtgccaacagcctttgtgcctgctccacctgtggcacctgtcccagctccagccccaatgccccctgtgcatcccccacctcccatggaagatgagcccacctccaaaaaactgaagacagaggacagcctcatgccagaggaggagttcctgcgcagaaacaagggtccagtgtccatcaaagtccaggtgcccaacatgcaggataagacggaatggaaactgaatgggcaggtgctggtcttcaccctcccactcacggaccaggtctctgtcattaaggtgaagattcatgaagccacaggcatgcctgcagggaaacagaagctacagtatgagggtatcttcatcaaagattccaactcactggcttactacaacatggccaatggcgcagtcatccacctggccctcaaggagagaggcgggaggaagaagtag
Sequence Length
2382
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
81,678 Da
NCBI Official Full Name
Homo sapiens splicing factor 3a, subunit 1, 120kDa, mRNA
NCBI Official Synonym Full Names
splicing factor 3a subunit 1
NCBI Official Symbol
SF3A1
NCBI Official Synonym Symbols
PRP21; PRPF21; SAP114; SF3A120
NCBI Protein Information
splicing factor 3A subunit 1
UniProt Protein Name
Splicing factor 3A subunit 1
Protein Family
UniProt Gene Name
SF3A1
UniProt Synonym Gene Names
SAP114; SAP 114
UniProt Entry Name
SF3A1_HUMAN
NCBI Description
This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing. [provided by RefSeq, Aug 2014]
Uniprot Description
SF3A1: subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Protein type: Nuclear receptor co-regulator; RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: nucleoplasm; snRNP U2; spliceosome
Molecular Function: protein binding; RNA binding
Biological Process: mRNA processing; nuclear mRNA 3'-splice site recognition; nuclear mRNA splicing, via spliceosome; regulation of alternative nuclear mRNA splicing, via spliceosome
Research Articles on SF3A1
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Product Notes
The SF3A1 sf3a1 (Catalog #AAA1270112) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgccggccg gacccgtgca ggcggtgccc ccgccgccgc ccgtgcccac ggagcccaaa cagcccacag aagaagaagc atcttcaaag gaggattctg caccttctaa gccagttgtg gggattattt accctcctcc agaggtcaga aatattgttg acaagactgc cagctttgtg gccagaaacg ggcctgaatt tgaagctagg atccgacaga acgagatcaa caaccccaag ttcaactttc tgaaccccaa tgacccttac catgcctact accgccacaa ggtcagcgag ttcaaggaag ggaaggctca ggagccgtcc gccgccatcc ccaaggtcat gcagcagcag cagcagacca cccagcagca gctgccccag aaggtccaag cccaagtaat ccaagagacc atcgtgccca aagagcctcc tcctgagttt gagttcattg ctgatcctcc ctctatctca gccttcgact tggatgtggt gaagctgacg gctcagtttg tggccaggaa tgggcgccag tttctgaccc agctgatgca gaaagagcag cgcaactacc agtttgactt tctccgccca cagcacagcc tcttcaacta cttcacgaag ctagtggaac agtacaccaa gatcttgatt ccacccaaag gtttattttc aaagctcaag aaagaggctg aaaacccccg agaagttttg gatcaggtgt gttaccgagt ggaatgggcc aaattccagg aacgtgagag gaagaaggaa gaagaggaga aggagaagga gcgggtggcc tatgctcaga tcgactggca tgattttgtg gtggtggaaa cagtggactt ccaacccaat gagcaaggga acttccctcc ccccaccacg ccagaggagc tgggggcccg aatcctcatt caggagcgct atgaaaagtt tggggagagt gaggaagttg agatggaggt cgagtctgat gaggaggatg acaaacagga gaaggcggag gagcctcctt cccagctgga ccaggacacc caagtacaag atatggatga gggttcagat gatgaagaag aagggcagaa agtgccccca cccccagaga cacccatgcc tccacctctg cccccaactc cagaccaagt cattgtccgc aaggattatg atcccaaagc ctccaagccc ttgcctccag cccctgctcc agatgagtat cttgtgtccc ccattactgg ggagaagatc cccgccagca aaatgcagga acacatgcgc attggacttc ttgaccctcg ctggctggag cagcgggatc gctccatccg tgagaagcag agcgatgatg aggtgtacgc accaggtctg gatattgaga gcagcttgaa gcagttggct gagcggcgta ctgacatctt cggtgtagag gaaacagcca ttggtaagaa gatcggtgag gaggagatcc agaagccaga ggaaaaggtg acctgggatg gccactcagg cagcatggcc cggacccagc aggctgccca ggccaacatc accctccagg agcagattga ggccattcac aaggccaaag gcctggtgcc agaggatgac actaaagaga agattggccc cagcaagccc aatgaaatcc ctcaacagcc accgccacca tcttcagcca ccaacatccc cagctcggct ccacccatca cttcagtgcc ccgaccaccc acaatgccac ctccagttcg tactacagtt gtctccgcag tacccgtcat gccccggccc ccaatggcat ctgtggtccg gctgccccca ggctcagtga tcgcccccat gccgcccatc atccacgcgc ccagaatcaa cgtggtgccc atgcctccct cggcccctcc tattatggcc ccccgcccac cccccatgat tgtgccaaca gcctttgtgc ctgctccacc tgtggcacct gtcccagctc cagccccaat gccccctgtg catcccccac ctcccatgga agatgagccc acctccaaaa aactgaagac agaggacagc ctcatgccag aggaggagtt cctgcgcaga aacaagggtc cagtgtccat caaagtccag gtgcccaaca tgcaggataa gacggaatgg aaactgaatg ggcaggtgct ggtcttcacc ctcccactca cggaccaggt ctctgtcatt aaggtgaaga ttcatgaagc cacaggcatg cctgcaggga aacagaagct acagtatgag ggtatcttca tcaaagattc caactcactg gcttactaca acatggccaa tggcgcagtc atccacctgg ccctcaagga gagaggcggg aggaagaagt ag. It is sometimes possible for the material contained within the vial of "SF3A1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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