SLC35B3 cdna clone
SLC35B3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the solute carrier family. The encoded protein is involved in the transport of 3-prime phosphoadenosine 5-prime phosphosulfate (PAPS) from the nucleus or the cytosol to the Golgi lumen. This gene has been reported to be expressed preferentially in the human colon tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
SLC35B3: Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon. Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p24.3
Cellular Component: Golgi membrane; integral to endoplasmic reticulum membrane; integral to Golgi membrane
Molecular Function: 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
Biological Process: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; positive regulation of defense response to virus by host
Research Articles on SLC35B3
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Product Notes
The SLC35B3 slc35b3 (Catalog #AAA1268357) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggacttga cacagcaagc aaaagacata cagaacataa cagtccagga aaccaacaaa aataactctg aaagcattga atgcagcaaa ataacaatgg atctcaagtt caacaattcc aggaaatata tttctatcac tgtgccatcc aaaacccaaa caatgtcacc acacatcaag tcagttgacg acgttgtggt acttggcatg aatctcagca agtttaacaa acttactcag tttttcatat gtgttgctgg agtttttgta ttttacctaa tttatgggta tttacaggaa ttaatatttt cagtggaggg ttttaagtcc tgtggctggt accttacctt agtgcagttt gccttttact ccatatttgg cctaatagaa cttcagctta ttcaggacaa aaggaggaga ataccaggaa aaacctacat gataatagct tttctaactg tgggtactat ggggttatca aacacttcct tgggctacct gaattaccct acccaagtca tcttcaagtg ctgcaaattg attcctgtta tgctaggagg agtttttatt caaggaaagc gttataatgt tgcagatgtg tctgctgcca tatgtatgag ccttggcctg atatggttta ccctcgctga cagcacaact gcaccaaatt tcaacctgac gggtgtggtg cttatttccc tggcactatg tgcagatgcc gtcattggaa atgttcaaga gaaagctatg aaacttcata atgcttctaa ttctgaaatg gtattgtatt cgtattcaat tggttttgta tacattttac tgggattgac atgcactagt ggattaggcc ctgcagtaac attttgtgca aagaatccag ttcggaccta tggttatgcg ttcctttttt ccctcactgg atattttgga atctcctttg ttctggcttt gattaaaatt tttggtgcac ttattgctgt aacagtgaca acaggaagaa aagcaatgac cattgtactt tcgtttatat tctttgctaa accattcacg tttcagtatg tatggtctgg tttgttagtt gtccttggta tatttctcaa tgtttacagc aaaaatatgg ataaaataag actaccatca ctgtatgatt tgataaacaa atcagtggaa gcaagaaagt caaggacgct ggcacagact gtatag. It is sometimes possible for the material contained within the vial of "SLC35B3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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