ASB3 cdna clone
ASB3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2011]
Uniprot Description
ASB3: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 2p16.2
Cellular Component: cytoplasm; nucleus; ubiquitin ligase complex
Molecular Function: protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity
Research Articles on ASB3
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Product Notes
The ASB3 asb3 (Catalog #AAA1268326) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggatttta cagaggctta cgcggacacg tgctctacag ttggacttgc tgccagggaa ggcaatgtta aagtcttaag gaaactgctc aaaaagggcc gaagtgtcga tgttgctgat aacaggggat ggatgccaat tcatgaagca gcttatcaca actctgtaga atgtttgcaa atgttaatta atgcagattc atctgaaaac tacattaaga tgaagacctt tgaaggtttc tgtgctttgc atctcgctgc aagtcaagga cattggaaaa tcgtacagat tcttttagaa gctggggcag atcctaatgc aactacttta gaagaaacga caccattgtt tttagctgtt gaaaatggac agatagatgt gttaaggctg ttgcttcaac acggagcaaa tgttaatgga tcccattcta tgtgtggatg gaactccttg caccaggctt cttttcagga aaatgctgag atcataaaat tgcttcttag aaaaggagca aacaaggaat gccaggatga ctttggaatc acacctttat ttgtggctgc tcagtatggc aagctagaaa gcttgagcat acttatttca tcgggtgcaa atgtcaattg tcaagccttg gacaaagcta cacccttgtt cattgctgct caagagggac acacaaaatg tgtggagctt ttgctctcca gtggggcaga tcctgatctt tactgtaatg aggacagttg gcagttacct attcatgcag ctgcacaaat gggccataca aaaatcttgg acttgttaat accacttact aaccgggcct gtgacactgg gctaaacaaa gtaagccctg tttactcagc agtgtttggg ggacatgaag attgcctaga aatattactc cggaatggct acagcccaga cgcccaggcg tgccttgttt ttggattcag ttctcctgtg tgcatggctt tccaaaagga ctgtgagttc tttggaattg tgaacattct tttgaaatat ggagcccaga taaatgaact tcatttggca tactgcctga agtacgagaa gttttcgata tttcgctact ttttgaggaa aggttgctca ttgggaccat ggaaccatat atatgaattt gtaaatcatg caattaaagc acaagcaaaa tataaggagt ggttgccaca tcttctggtt gctggatttg acccactgat tctactgtgc aattcttgga ttgactcagt cagcattgac acccttatct tcactttgga gtttactaat tggaagacac ttgcaccagc tgttgaaagg atgctctctg ctcgtgcctc aaacgcttgg attctacagc aacatattgc cactgttcca tccctgaccc atctttgtcg tttggaaatt cggtccagtc taaaatcaga acgtctacgg tctgacagtt atattagtca gctgccactt cccagaagcc tacataatta tttgctctat gaagacgttc tgaggatgta tgaagttcca gaactggcag ctattcaaga tggataa. It is sometimes possible for the material contained within the vial of "ASB3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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